ModCRE DB

Transcription factor

Q92570 - NR4A3

Nuclear receptor subfamily 4 group A member 3 (Mitogen-induced nuclear orphan receptor) (Neuron-derived orphan receptor 1) (Nuclear hormone receptor NOR-1) (Translocated in extraskeletal chondrosarcoma)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 626 aa

50 Generated PWM 22 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)36
MotifPredictionSourceDNA bindingSupportLogoActions
M03939_2.00 NN 70-40% CisBP TAAAGGTCA 64.4% identity Open · Scan
M05660_2.00 NN 70-40% CisBP GATGTGGGTCAGTGGGTCAG 60.2% identity Open · Scan
MA1531.1 NN 70-40% JASPAR GGGTCAGTAGGTCAG 60.2% identity Open · Scan
MA1532.1 NN 70-40% JASPAR GGGTTAGTGGGTCAT 60.2% identity Open · Scan
M05590_2.00 NN 70-40% CisBP TTCAAGGTCAC 59.3% identity Open · Scan
MA0071.1 NN 70-40% JASPAR ATCAAGGTCA 58.3% identity Open · Scan
M02388_2.00 NN 70-40% CisBP GAGGTCA 56.9% identity Open · Scan
M06413_2.00 NN 70-40% CisBP AAATAGGTCA 56.9% identity Open · Scan
M00689_2.00 NN 70-40% CisBP AAAGATCAA 56.6% identity Open · Scan
M00812_2.00 NN 70-40% CisBP AGAGGTCACG 56.3% identity Open · Scan
M02413_2.00 NN 70-40% CisBP CGAGATCAA 56.3% identity Open · Scan
M05599_2.00 NN 70-40% CisBP AAAGGTCAA 56.3% identity Open · Scan
MA1535.1 NN 70-40% JASPAR CGAGGTCAC 56.3% identity Open · Scan
M06417_2.00 NN 70-40% CisBP CAGTCCGAAGGTCACCGC 55.8% identity Open · Scan
M03426_2.00 NN 70-40% CisBP GGGGTCAAAGTCCAAT 55.7% identity Open · Scan
M00820_2.00 NN 70-40% CisBP TAGGTCACC 55.5% identity Open · Scan
M05621_2.00 NN 70-40% CisBP TAGGTCATGACCTA 55.5% identity Open · Scan
MA1150.1 NN 70-40% JASPAR AATTAGGTCAC 55.5% identity Open · Scan
MA1151.1 NN 70-40% JASPAR ATAAGTAGGTCA 55.5% identity Open · Scan
M05669_2.00 NN 70-40% CisBP GAGGTCAT 55.4% identity Open · Scan
M08226_2.00 NN 70-40% CisBP CAAGGTCA 55.4% identity Open · Scan
MA0504.1 NN 70-40% JASPAR AGGGGTCAGAGGTCA 55.4% identity Open · Scan
MA1540.1 NN 70-40% JASPAR GTCAAGGTCAC 55.4% identity Open · Scan
M05635_2.00 NN 70-40% CisBP GTGACCTCAATGAGGTCAC 55.3% identity Open · Scan
M11192_2.00 NN 70-40% CisBP GGGGTCACG 55.1% identity Open · Scan
M02392_2.00 NN 70-40% CisBP GAGGTCAA 55.0% identity Open · Scan
M09609_2.00 NN 70-40% CisBP CCAGGAACAG 54.8% identity Open · Scan
M09616_2.00 NN 70-40% CisBP TTCAAGGTCA 54.6% identity Open · Scan
MA0160.1 NN 70-40% JASPAR AAGGTCAC 54.6% identity Open · Scan
MA0505.1 NN 70-40% JASPAR AAGTTCAAGGTCAGC 54.6% identity Open · Scan
M05584_2.00 NN 70-40% CisBP AGAGGTCACGACCTCT 52.7% identity Open · Scan
MA1550.1 NN 70-40% JASPAR AGGGGTCAAAGGTCAA 52.7% identity Open · Scan
M09275_2.00 NN 70-40% CisBP GGGTCACTTCAGGTCAG 52.1% identity Open · Scan
M02405_2.00 NN 70-40% CisBP AGAGGTCAGT 51.3% identity Open · Scan
MA1110.1 NN 70-40% JASPAR TCAATGACCTA 50.6% identity Open · Scan
MA1541.1 NN 70-40% JASPAR GTCAAGTTCAAGGTCAA 50.6% identity Open · Scan
ModCRE14
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q92570_NR4A3_HUMAN:292:365_1r0o_A_1 ModCRE Homology model AAAGGTCAATGACCTTT Region 292-365 · 1 3D model Open · Scan
DIMER_sp_Q92570_NR4A3_HUMAN:292:365_2han_A_1 ModCRE Homology model AAAAGGTCAATGACCTTTT Region 292-365 · 1 3D model Open · Scan
DIMER_sp_Q92570_NR4A3_HUMAN:292:365_4cn3_B_1 ModCRE Homology model TTGACCTTTGACCT Region 292-365 · 1 3D model Open · Scan
DIMER_sp_Q92570_NR4A3_HUMAN:292:365_6fbr_A_1 ModCRE Homology model AAAGGTCAAAAGTCATT Region 292-365 · 1 3D model Open · Scan
DIMER_sp_Q92570_NR4A3_HUMAN:292:369_4cn2_D_1 ModCRE Homology model AGAGGTCAAAGGTTAAT Region 292-369 · 1 3D model Open · Scan
TFS_sp_Q92570_NR4A3_HUMAN:290:375_6lc1_J_1 ModCRE Homology model ATGACCTTTTCATATAAAGGTCATA Region 290-375 · 1 3D model Open · Scan
TFS_sp_Q92570_NR4A3_HUMAN:290:378_1cit_A_1 ModCRE Homology model TTTATGACCTTTTAAA Region 290-378 · 1 3D model Open · Scan
TFS_sp_Q92570_NR4A3_HUMAN:290:625_7wnh_A_1 ModCRE Homology model TTTATGACCTTTTAAA Region 290-625 · 1 3D model Open · Scan
TFS_sp_Q92570_NR4A3_HUMAN:292:365_1r0o_A_1 ModCRE Homology model AAAGGTCAATAACCTTT Region 292-365 · 1 3D model Open · Scan
TFS_sp_Q92570_NR4A3_HUMAN:292:369_4cn2_D_1 ModCRE Homology model TTTTAAAGGTCATT Region 292-369 · 1 3D model Open · Scan
TFS_sp_Q92570_NR4A3_HUMAN:292:375_6l6l_A_1 ModCRE Homology model AAAGGTCATTTAATGACCTT Region 292-375 · 1 3D model Open · Scan
TFS_sp_Q92570_NR4A3_HUMAN:292:375_6l6q_B_1 ModCRE Homology model TTTGACCTTTAAAGGTCATT Region 292-375 · 1 3D model Open · Scan
TFS_sp_Q92570_NR4A3_HUMAN:436:619_5uan_B_1 ModCRE Homology model AAAACCCCTTTTTA Region 436-619 · 1 3D model Open · Scan
TFS_sp_Q92570_NR4A3_HUMAN:451:606_5uan_A_1 ModCRE Homology model ATGCATTC Region 451-606 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 626 aa
288-625

Region 288-625 14 PWM

Residues
338 aa
Domains
PF00105 · Double treble clef zinc finger, C4 type PF00104 · Ligand-binding domain of nuclear hormone receptor
3D models
22 active PDBs · 10 summary rows
Templates
1CIT, 1R0O, 2HAN, 3DZU, 3DZY, 4CN2, 4CN3, 4NQA, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
22 active PDB models 10 summary rows
Region 288-62522 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q92570_NR4A3_HUMAN:290:375_6lc1_J_1 6lc1 290-375 View model · PDB
Predicted = Low DIMER_sp_Q92570_NR4A3_HUMAN:292:365_1r0o_A_1 1r0o 292-365 View model · PDB
Predicted = Low DIMER_sp_Q92570_NR4A3_HUMAN:292:365_2han_A_1 2han 292-365 View model · PDB
Predicted = Low DIMER_sp_Q92570_NR4A3_HUMAN:292:365_4cn3_B_1 4cn3 292-365 View model · PDB
Predicted = Low DIMER_sp_Q92570_NR4A3_HUMAN:292:365_6fbr_A_1 6fbr 292-365 View model · PDB
Predicted = Low DIMER_sp_Q92570_NR4A3_HUMAN:292:369_4cn2_D_1 4cn2 292-369 View model · PDB
Predicted = Low DIMER_sp_Q92570_NR4A3_HUMAN:292:375_6l6l_A_1 6l6l 292-375 View model · PDB
Predicted = Low DIMER_sp_Q92570_NR4A3_HUMAN:292:375_6l6q_B_1 6l6q 292-375 View model · PDB
Predicted = Low DIMER_sp_Q92570_NR4A3_HUMAN:292:606_4nqa_A_1 4nqa 292-606 View model · PDB
Predicted = Low DIMER_sp_Q92570_NR4A3_HUMAN:292:619_5uan_B_1 5uan 292-619 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:290:375_6lc1_J_1 6lc1 290-375 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:290:378_1cit_A_1 1cit 290-378 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:290:625_7wnh_A_1 7wnh 290-625 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:292:365_1r0o_A_1 1r0o 292-365 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:292:369_4cn2_D_1 4cn2 292-369 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:292:375_6l6l_A_1 6l6l 292-375 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:292:375_6l6q_B_1 6l6q 292-375 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:436:619_5uan_B_1 5uan 436-619 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:451:606_3dzu_A_1 3dzu 451-606 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:451:606_3dzy_A_1 3dzy 451-606 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:451:606_4nqa_A_1 4nqa 451-606 View model · PDB
Predicted = Low TFS_sp_Q92570_NR4A3_HUMAN:451:606_5uan_A_1 5uan 451-606 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 6l6q 289:625 292,292 375,375 P:A,B · DNA:C,F 98.8% / 100.0% 98,98 View · PDB DIMER_sp_Q92570_NR4A3_HUMAN:292:375_6l6q_B_1
2 6l6l 289:625 292,292 375,374 P:A,B · DNA:C,D 98.8% / 100.0% 98,98 View · PDB DIMER_sp_Q92570_NR4A3_HUMAN:292:375_6l6l_A_1
2 6l6q 289:625 292,292 375,375 P:A,B · DNA:C,F 98.8% / 100.0% 98,98 View · PDB TFS_sp_Q92570_NR4A3_HUMAN:292:375_6l6q_B_1
3 6l6l 289:625 292,292 375,374 P:A,B · DNA:C,D 98.8% / 100.0% 98,98 View · PDB TFS_sp_Q92570_NR4A3_HUMAN:292:375_6l6l_A_1
3 6lc1 289:625 292,290 376,375 P:G,J · DNA:I,L 93.0% / 98.8% 98,100 View · PDB DIMER_sp_Q92570_NR4A3_HUMAN:290:375_6lc1_J_1
4 6lc1 289:625 292,290 376,375 P:G,J · DNA:I,L 93.0% / 98.8% 98,100 View · PDB TFS_sp_Q92570_NR4A3_HUMAN:290:375_6lc1_J_1
5 1cit 289:625 290 378 P:A · DNA:B,C 92.1% / 98.9% 100 View · PDB TFS_sp_Q92570_NR4A3_HUMAN:290:378_1cit_A_1
1 7wnh 289:625 290 625 P:A · DNA:E,F 69.0% / 77.8% 98 View · PDB TFS_sp_Q92570_NR4A3_HUMAN:290:625_7wnh_A_1
5 5uan 289:625 292,292 606,619 P:A,B · DNA:E,F 32.7% / 48.6% 92,97 View · PDB DIMER_sp_Q92570_NR4A3_HUMAN:292:619_5uan_B_1
4 4nqa 289:625 292,288 606,392 P:A,B · DNA:E,F 32.3% / 50.8% 91,28 View · PDB DIMER_sp_Q92570_NR4A3_HUMAN:292:606_4nqa_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
291-359PF00105Double treble clef zinc finger, C4 typeoverlaps 288-625
434-606PF00104Ligand-binding domain of nuclear hormone receptoroverlaps 288-625