ModCRE DB

Transcription factor

Q969J2 - ZKSCAN4

Zinc finger protein with KRAB and SCAN domains 4 (P373c6.1) (Zinc finger protein 307) (Zinc finger protein 427)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 545 aa

79 Generated PWM 10 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)75
MotifPredictionSourceDNA bindingSupportLogoActions
M00960_2.00 NN 70-40% CisBP TGCATCCC 67.0% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 66.2% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 65.8% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 64.7% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 64.7% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 64.7% identity Open · Scan
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 64.5% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 63.5% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 63.5% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 63.5% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 62.3% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 61.6% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 60.9% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 60.3% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 60.0% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 59.0% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 58.8% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 58.7% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 57.1% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 56.9% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 55.6% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 55.2% identity Open · Scan
M07650_2.00 NN 70-40% CisBP GGTCTATAAAAGGGGGGCCGCGGGGGGG 54.7% identity Open · Scan
M08365_2.00 NN 70-40% CisBP GCCAGCAGCCATCAG 54.6% identity Open · Scan
M08934_2.00 NN 70-40% CisBP GCTGTACCTGCTTATTAGGC 54.2% identity Open · Scan
M07777_2.00 NN 70-40% CisBP GCCAATTTCCGTGGTGTAAAT 54.0% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 53.8% identity Open · Scan
M07700_2.00 NN 70-40% CisBP ATGTTGTGAGGAAGCCCA 53.8% identity Open · Scan
M07689_2.00 NN 70-40% CisBP ACCCAGGCTCCTTCCATCTTGTGGCTC 53.5% identity Open · Scan
M08255_2.00 NN 70-40% CisBP CTCTTCCGGT 53.4% identity Open · Scan
M00769_2.00 NN 70-40% CisBP ACTCCCCC 53.2% identity Open · Scan
M07658_2.00 NN 70-40% CisBP CCGCCGCAGCCGCCG 53.1% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 52.9% identity Open · Scan
M08347_2.00 NN 70-40% CisBP GCCCTGGGCAGC 52.9% identity Open · Scan
M00134_2.00 NN 70-40% CisBP GCCACGCCCA 52.5% identity Open · Scan
M07598_2.00 NN 70-40% CisBP CTGACAATACCAAGTGTTGAC 52.5% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 52.5% identity Open · Scan
M08256_2.00 NN 70-40% CisBP GTGCCTT 52.4% identity Open · Scan
M05844_2.00 NN 70-40% CisBP TCACCTGT 52.0% identity Open · Scan
M07635_2.00 NN 70-40% CisBP AAGTTTTCTTGTATTATATCT 52.0% identity Open · Scan
M08300_2.00 NN 70-40% CisBP CTGCCCAATTCAT 52.0% identity Open · Scan
MA0103.1 NN 70-40% JASPAR CACCTG 52.0% identity Open · Scan
MA0103.2 NN 70-40% JASPAR CCTCACCTG 52.0% identity Open · Scan
M08944_2.00 NN 70-40% CisBP TACCATGCTGTTTTGATTAC 51.7% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 51.5% identity Open · Scan
MA1589.1 NN 70-40% JASPAR TAGGAGTGGAATTGCTGGGTC 51.5% identity Open · Scan
M07678_2.00 NN 70-40% CisBP CCCGCCCCCTCCTCCCCCTTCCCACCC 51.3% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 51.2% identity Open · Scan
M01538_2.00 NN 70-40% CisBP GCCCCTGA 51.1% identity Open · Scan
M07588_2.00 NN 70-40% CisBP TCCTTCCCTCTTTCC 51.1% identity Open · Scan
M07693_2.00 NN 70-40% CisBP CTCCTGTGTGTGCCTTGGCTG 51.1% identity Open · Scan
M07714_2.00 NN 70-40% CisBP AGCCCATTGGGGCCTATGCCC 51.1% identity Open · Scan
M08245_2.00 NN 70-40% CisBP TGGTGCCTTATTCCC 51.1% identity Open · Scan
M08540_2.00 NN 70-40% CisBP CCCCT 51.1% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 51.1% identity Open · Scan
M01440_2.00 NN 70-40% CisBP TACGCCAC 51.0% identity Open · Scan
M03671_2.00 NN 70-40% CisBP ATTACCATACAAGTGCAC 50.8% identity Open · Scan
M08279_2.00 NN 70-40% CisBP CCTCCCTCC 50.8% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 50.8% identity Open · Scan
M00764_2.00 NN 70-40% CisBP GTCTACAC 50.7% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 50.6% identity Open · Scan
M08371_2.00 NN 70-40% CisBP CCAGACTTGTCCTCT 50.6% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 50.4% identity Open · Scan
M07761_2.00 NN 70-40% CisBP CTGATTATTCACCCA 50.4% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 50.4% identity Open · Scan
M08860_2.00 NN 70-40% CisBP TCTTATAAGGGCACTAATCCCATT 50.4% identity Open · Scan
M07699_2.00 NN 70-40% CisBP GGTTTAT 50.2% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 50.2% identity Open · Scan
M04463_2.00 NN 70-40% CisBP CACCACGCCCA 50.0% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 50.0% identity Open · Scan
M07712_2.00 NN 70-40% CisBP ACATTTTTTTAATCTAAAAAAACATTTACA 50.0% identity Open · Scan
MA0039.1 NN 70-40% JASPAR TAAAGGAAGG 50.0% identity Open · Scan
MA0039.3 NN 70-40% JASPAR CCACACCCTGC 50.0% identity Open · Scan
MA0740.1 NN 70-40% JASPAR GGCCACGCCCCCTT 50.0% identity Open · Scan
MA1515.1 NN 70-40% JASPAR CACCACGCCCA 50.0% identity Open · Scan
ModCRE4
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q969J2_ZKSC4_HUMAN:325:426_2jp9_A_1 ModCRE Homology model GCCGGGGGAGATCCGCA Region 325-426 · 1 3D model Open · Scan
TFS_sp_Q969J2_ZKSC4_HUMAN:345:454_5egb_A_1 ModCRE Homology model CCCCCCGGGGGACCGGGG Region 345-454 · 1 3D model Open · Scan
TFS_sp_Q969J2_ZKSC4_HUMAN:347:454_5eh2_F_1 ModCRE Homology model CCCCCGGGGGGGGGTCAAG Region 347-454 · 1 3D model Open · Scan
TFS_sp_Q969J2_ZKSC4_HUMAN:374:454_1a1g_A_1 ModCRE Homology model GGGCGGGGCC Region 374-454 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 545 aa
286-541

Region 286-541 4 PWM

Residues
256 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
10 active PDBs · 6 summary rows
Templates
1A1G, 1LLM, 2I13, 2JP9, 5EGB, 5EH2, 5EI9, 5V3J, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
10 active PDB models 6 summary rows
Region 286-54110 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q969J2_ZKSC4_HUMAN:374:425_1llm_D_1 1llm 374-425 View model · PDB
Predicted = Low TFS_sp_Q969J2_ZKSC4_HUMAN:286:537_5wjq_D_1 5wjq 286-537 View model · PDB
Predicted = Low TFS_sp_Q969J2_ZKSC4_HUMAN:306:541_5v3j_E_1 5v3j 306-541 View model · PDB
Predicted = Low TFS_sp_Q969J2_ZKSC4_HUMAN:306:541_5v3m_C_1 5v3m 306-541 View model · PDB
Predicted = Low TFS_sp_Q969J2_ZKSC4_HUMAN:307:454_2i13_A_1 2i13 307-454 View model · PDB
Predicted = Low TFS_sp_Q969J2_ZKSC4_HUMAN:325:426_2jp9_A_1 2jp9 325-426 View model · PDB
Predicted = Low TFS_sp_Q969J2_ZKSC4_HUMAN:345:454_5egb_A_1 5egb 345-454 View model · PDB
Predicted = Low TFS_sp_Q969J2_ZKSC4_HUMAN:345:454_5ei9_E_1 5ei9 345-454 View model · PDB
Predicted = Low TFS_sp_Q969J2_ZKSC4_HUMAN:347:454_5eh2_F_1 5eh2 347-454 View model · PDB
Predicted = Low TFS_sp_Q969J2_ZKSC4_HUMAN:374:454_1a1g_A_1 1a1g 374-454 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 5ei9 286:541 345 454 P:E · DNA:A,B 59.1% / 70.0% 99 View · PDB TFS_sp_Q969J2_ZKSC4_HUMAN:345:454_5ei9_E_1
4 2i13 286:541 307 454 P:A · DNA:C,D 54.7% / 68.2% 96 View · PDB TFS_sp_Q969J2_ZKSC4_HUMAN:307:454_2i13_A_1
1 1llm 286:541 374,374 425,425 P:C,D · DNA:A,B 48.1% / 63.5% 59,61 View · PDB DIMER_sp_Q969J2_ZKSC4_HUMAN:374:425_1llm_D_1
1 5v3m 286:541 306 541 P:C · DNA:A,B 44.3% / 61.2% 85 View · PDB TFS_sp_Q969J2_ZKSC4_HUMAN:306:541_5v3m_C_1
2 5v3j 286:541 306 541 P:E · DNA:A,B 44.3% / 61.2% 85 View · PDB TFS_sp_Q969J2_ZKSC4_HUMAN:306:541_5v3j_E_1
3 5wjq 286:541 286 537 P:D · DNA:A,B 41.9% / 58.9% 89 View · PDB TFS_sp_Q969J2_ZKSC4_HUMAN:286:537_5wjq_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
49-137PF02023SCAN domainNo overlap with loaded model regions
223-260PF01352KRAB boxNo overlap with loaded model regions
320-342PF00096Zinc finger, C2H2 typeoverlaps 286-541
348-370PF00096Zinc finger, C2H2 typeoverlaps 286-541
376-398PF00096Zinc finger, C2H2 typeoverlaps 286-541
404-426PF00096Zinc finger, C2H2 typeoverlaps 286-541
432-454PF00096Zinc finger, C2H2 typeoverlaps 286-541
487-509PF00096Zinc finger, C2H2 typeoverlaps 286-541
515-537PF00096Zinc finger, C2H2 typeoverlaps 286-541