ModCRE DB

Transcription factor

Q96JF6 - ZNF594

Zinc finger protein 594 (Zinc finger protein HZF18)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 807 aa

61 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M08354_2.00 Known CisBP AGCCGCTCTCACCCC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)54
MotifPredictionSourceDNA bindingSupportLogoActions
M00939_2.00 NN 70-40% CisBP CCACCTCA 65.8% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 65.8% identity Open · Scan
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 64.0% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 63.6% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 63.5% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 63.5% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 63.5% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 62.3% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 62.3% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 62.3% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 61.2% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 61.1% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 61.1% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 61.1% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 60.5% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 60.4% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 60.0% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 59.7% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 58.6% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 57.8% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 57.8% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 56.7% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 56.7% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 56.2% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 56.0% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 55.9% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 55.7% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 55.4% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 54.5% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 53.4% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 53.2% identity Open · Scan
M08274_2.00 NN 70-40% CisBP TTACTTGCAGCCCAACGCATTCCTAAC 52.8% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 52.1% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 51.6% identity Open · Scan
M00142_2.00 NN 70-40% CisBP GTGCTCCT 51.5% identity Open · Scan
M08309_2.00 NN 70-40% CisBP AAAAACCCCCCTGCAGAGCCCAGCCCT 51.5% identity Open · Scan
MA1515.1 NN 70-40% JASPAR CACCACGCCCA 51.3% identity Open · Scan
M04610_2.00 NN 70-40% CisBP CGGCGACGCGAACAC 51.2% identity Open · Scan
M07635_2.00 NN 70-40% CisBP AAGTTTTCTTGTATTATATCT 51.2% identity Open · Scan
M07650_2.00 NN 70-40% CisBP GGTCTATAAAAGGGGGGCCGCGGGGGGG 51.2% identity Open · Scan
M07733_2.00 NN 70-40% CisBP TCTTTCTCTCTCTCC 51.1% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 51.0% identity Open · Scan
M07566_2.00 NN 70-40% CisBP TCAAACCATCCTTGC 50.3% identity Open · Scan
M07700_2.00 NN 70-40% CisBP ATGTTGTGAGGAAGCCCA 50.1% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 50.1% identity Open · Scan
M00019_2.00 NN 70-40% CisBP ACCCCTAATT 50.0% identity Open · Scan
M00217_2.00 NN 70-40% CisBP TTACTCAATAT 50.0% identity Open · Scan
M01457_2.00 NN 70-40% CisBP GCGCACGGAC 50.0% identity Open · Scan
M01531_2.00 NN 70-40% CisBP CCCCCCCTAAAT 50.0% identity Open · Scan
M04463_2.00 NN 70-40% CisBP CACCACGCCCA 50.0% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 50.0% identity Open · Scan
MA0039.1 NN 70-40% JASPAR TAAAGGAAGG 50.0% identity Open · Scan
MA0039.3 NN 70-40% JASPAR CCACACCCTGC 50.0% identity Open · Scan
MA0746.1 NN 70-40% JASPAR GCCACGCCCCC 50.0% identity Open · Scan
ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q96JF6_ZN594_HUMAN:458:509_1llm_D_1 ModCRE Homology model CCGCGCGGCGAT Region 458-509 · 1 3D model Open · Scan
TFS_sp_Q96JF6_ZN594_HUMAN:237:511_5wjq_D_1 ModCRE Homology model TTCCCTTCACGCCCCCCCCCCCCCGGCC Region 237-511 · 1 3D model Open · Scan
TFS_sp_Q96JF6_ZN594_HUMAN:357:510_2i13_A_1 ModCRE Homology model TCACGGCAGTAGCTCTATAGT Region 357-510 · 1 3D model Open · Scan
TFS_sp_Q96JF6_ZN594_HUMAN:376:670_7w1m_H_1 ModCRE Homology model TAAAGTCGGCGGCGGCCACCGGGGGAAGTCAAAGGGGCCCGGA Region 376-670 · 1 3D model Open · Scan
TFS_sp_Q96JF6_ZN594_HUMAN:459:730_5v3j_E_1 ModCRE Homology model GGCCCCCGGCCGCCCCTGGGCCCGCC Region 459-730 · 1 3D model Open · Scan
TFS_sp_Q96JF6_ZN594_HUMAN:459:730_5v3m_C_1 ModCRE Homology model GAAAGCCCCCCCCCCCCCCGCAACCT Region 459-730 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 807 aa
237-730

Region 237-730 6 PWM

Residues
494 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 237-7306 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q96JF6_ZN594_HUMAN:458:509_1llm_D_1 1llm 458-509 View model · PDB
Predicted = Low TFS_sp_Q96JF6_ZN594_HUMAN:237:511_5wjq_D_1 5wjq 237-511 View model · PDB
Predicted = Low TFS_sp_Q96JF6_ZN594_HUMAN:357:510_2i13_A_1 2i13 357-510 View model · PDB
Predicted = Low TFS_sp_Q96JF6_ZN594_HUMAN:376:670_7w1m_H_1 7w1m 376-670 View model · PDB
Predicted = Low TFS_sp_Q96JF6_ZN594_HUMAN:459:730_5v3j_E_1 5v3j 459-730 View model · PDB
Predicted = Low TFS_sp_Q96JF6_ZN594_HUMAN:459:730_5v3m_C_1 5v3m 459-730 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 350:733 357 510 P:A · DNA:C,D 56.5% / 70.1% 100 View · PDB TFS_sp_Q96JF6_ZN594_HUMAN:357:510_2i13_A_1
1 5v3m 350:733 459 730 P:C · DNA:A,B 51.8% / 67.0% 98 View · PDB TFS_sp_Q96JF6_ZN594_HUMAN:459:730_5v3m_C_1
2 5v3j 350:733 459 730 P:E · DNA:A,B 51.8% / 67.0% 98 View · PDB TFS_sp_Q96JF6_ZN594_HUMAN:459:730_5v3j_E_1
3 5wjq 350:733 237 511 P:D · DNA:A,B 51.4% / 66.9% 97 View · PDB TFS_sp_Q96JF6_ZN594_HUMAN:237:511_5wjq_D_1
1 1llm 350:733 458,458 509,509 P:C,D · DNA:A,B 46.2% / 61.5% 59,61 View · PDB DIMER_sp_Q96JF6_ZN594_HUMAN:458:509_1llm_D_1
5 7w1m 350:733 376 670 P:H · DNA:F,G 35.4% / 49.7% 91 View · PDB TFS_sp_Q96JF6_ZN594_HUMAN:376:670_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
127-149PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
155-177PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
183-205PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
211-233PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
239-261PF00096Zinc finger, C2H2 typeoverlaps 237-730
267-289PF00096Zinc finger, C2H2 typeoverlaps 237-730
296-317PF00096Zinc finger, C2H2 typeoverlaps 237-730
323-345PF00096Zinc finger, C2H2 typeoverlaps 237-730
404-426PF00096Zinc finger, C2H2 typeoverlaps 237-730
433-454PF00096Zinc finger, C2H2 typeoverlaps 237-730
460-482PF00096Zinc finger, C2H2 typeoverlaps 237-730
488-510PF00096Zinc finger, C2H2 typeoverlaps 237-730
570-590PF00096Zinc finger, C2H2 typeoverlaps 237-730
596-618PF00096Zinc finger, C2H2 typeoverlaps 237-730
624-646PF00096Zinc finger, C2H2 typeoverlaps 237-730
652-674PF00096Zinc finger, C2H2 typeoverlaps 237-730
680-702PF00096Zinc finger, C2H2 typeoverlaps 237-730
763-783PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions