Transcription factor

Q96JS8 - ZNF589

ZNF589 protein

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 240 aa

112 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)106

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	66.3% identity		Open · Scan
M07725_2.00	NN 70-40%	CisBP	AAGCACTGTACT	63.2% identity		Open · Scan
M07662_2.00	NN 70-40%	CisBP	CCTGTGTCCTCCCTGGTCCCC	62.2% identity		Open · Scan
MA1600.1	NN 70-40%	JASPAR	ATACAGTCCACCCCTTTA	61.2% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	60.2% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	60.2% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	60.0% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	60.0% identity		Open · Scan
M08903_2.00	NN 70-40%	CisBP	ATTCCATTCTATTCCATTCT	60.0% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	59.0% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	59.0% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	59.0% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	58.8% identity		Open · Scan
M07593_2.00	NN 70-40%	CisBP	AGATGAAGTCACCCCTCTTAC	58.8% identity		Open · Scan
M07688_2.00	NN 70-40%	CisBP	GAGCCCCAAGCA	58.6% identity		Open · Scan
M07645_2.00	NN 70-40%	CisBP	CTCCTT	57.9% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	57.4% identity		Open · Scan
M07579_2.00	NN 70-40%	CisBP	CATCTCCAGGA	57.2% identity		Open · Scan
M08279_2.00	NN 70-40%	CisBP	CCTCCCTCC	57.2% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	57.1% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	57.1% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	56.8% identity		Open · Scan
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	56.6% identity		Open · Scan
M07638_2.00	NN 70-40%	CisBP	TGCAGCTCCCTGCCC	56.6% identity		Open · Scan
M07702_2.00	NN 70-40%	CisBP	CTTCTTCCTTGG	56.6% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	56.3% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	56.3% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	56.1% identity		Open · Scan
M07646_2.00	NN 70-40%	CisBP	CTTTTTTTT	56.0% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	55.8% identity		Open · Scan
M08944_2.00	NN 70-40%	CisBP	TACCATGCTGTTTTGATTAC	55.7% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	55.5% identity		Open · Scan
M08292_2.00	NN 70-40%	CisBP	TGTATTCCTTGTCATGTGTGG	55.4% identity		Open · Scan
M08252_2.00	NN 70-40%	CisBP	CCGGCTCCAGCACCC	55.3% identity		Open · Scan
M07691_2.00	NN 70-40%	CisBP	CCTGCAGCCACCTTGGCCTTG	55.1% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	54.9% identity		Open · Scan
M04610_2.00	NN 70-40%	CisBP	CGGCGACGCGAACAC	54.8% identity		Open · Scan
M06050_2.00	NN 70-40%	CisBP	CACCTGT	54.8% identity		Open · Scan
M07762_2.00	NN 70-40%	CisBP	GCCGCGCACAGGCTTCTAGCC	54.8% identity		Open · Scan
M08245_2.00	NN 70-40%	CisBP	TGGTGCCTTATTCCC	54.8% identity		Open · Scan
M08887_2.00	NN 70-40%	CisBP	CCTCCTCCAGGAAGCCTTCCCTGA	54.8% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	54.6% identity		Open · Scan
M07598_2.00	NN 70-40%	CisBP	CTGACAATACCAAGTGTTGAC	54.6% identity		Open · Scan
M08371_2.00	NN 70-40%	CisBP	CCAGACTTGTCCTCT	54.4% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	54.1% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	54.1% identity		Open · Scan
M08917_2.00	NN 70-40%	CisBP	GCTGAGCCATGTGGGGTGCT	54.0% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	53.9% identity		Open · Scan
M00619_2.00	NN 70-40%	CisBP	TAAATCACGG	53.8% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	53.4% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	53.4% identity		Open · Scan
M08309_2.00	NN 70-40%	CisBP	AAAAACCCCCCTGCAGAGCCCAGCCCT	53.3% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	53.2% identity		Open · Scan
M07759_2.00	NN 70-40%	CisBP	GGAGCGCCCCTGCCCGGC	53.1% identity		Open · Scan
M08247_2.00	NN 70-40%	CisBP	AAAAATAACAAACGG	53.1% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	53.1% identity		Open · Scan
MA1594.1	NN 70-40%	JASPAR	AGGGGACATCACTACAGATCCCAC	53.1% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	52.9% identity		Open · Scan
M05853_2.00	NN 70-40%	CisBP	CCACCTTTAGCCATATCT	52.9% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	52.9% identity		Open · Scan
M08860_2.00	NN 70-40%	CisBP	TCTTATAAGGGCACTAATCCCATT	52.9% identity		Open · Scan
MA1589.1	NN 70-40%	JASPAR	TAGGAGTGGAATTGCTGGGTC	52.9% identity		Open · Scan
MA0528.1	NN 70-40%	JASPAR	GGAGGAGGAGGGGGAGGAGGA	52.8% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	52.6% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	52.6% identity		Open · Scan
M07707_2.00	NN 70-40%	CisBP	TCCCGC	52.6% identity		Open · Scan
M08274_2.00	NN 70-40%	CisBP	TTACTTGCAGCCCAACGCATTCCTAAC	52.6% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	52.6% identity		Open · Scan
M08914_2.00	NN 70-40%	CisBP	ATTTAGTCCATTTACATTTAATGT	52.6% identity		Open · Scan
M08347_2.00	NN 70-40%	CisBP	GCCCTGGGCAGC	52.4% identity		Open · Scan
M08399_2.00	NN 70-40%	CisBP	TACTCTGGGGCCACATGACTC	52.1% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	52.1% identity		Open · Scan
M08300_2.00	NN 70-40%	CisBP	CTGCCCAATTCAT	51.9% identity		Open · Scan
M04590_2.00	NN 70-40%	CisBP	TGCGCTAACCATTGC	51.7% identity		Open · Scan
M08291_2.00	NN 70-40%	CisBP	AATCCAGCCCTAGACTCTCCC	51.7% identity		Open · Scan
M08311_2.00	NN 70-40%	CisBP	CTGGAACAGAAGGGGCGA	51.7% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	51.7% identity		Open · Scan
M07590_2.00	NN 70-40%	CisBP	TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT	51.6% identity		Open · Scan
M07654_2.00	NN 70-40%	CisBP	TGCCCCCTGGTGGC	51.6% identity		Open · Scan
M07666_2.00	NN 70-40%	CisBP	ATCTAGCCCCTGCCTACC	51.6% identity		Open · Scan
M07667_2.00	NN 70-40%	CisBP	CCGCACAGGCCCCCGGGCCCC	51.6% identity		Open · Scan
M07777_2.00	NN 70-40%	CisBP	GCCAATTTCCGTGGTGTAAAT	51.6% identity		Open · Scan
M08859_2.00	NN 70-40%	CisBP	CATTTTTTCCTCCTAGGCCT	51.6% identity		Open · Scan
MA0744.1	NN 70-40%	JASPAR	ATGCAACAGGTGG	51.6% identity		Open · Scan
M04480_2.00	NN 70-40%	CisBP	ATTGATTACCCACCCTAC	51.4% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	51.4% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	51.4% identity		Open · Scan
M07601_2.00	NN 70-40%	CisBP	CAGATGCCGGCACCATGCTTC	51.2% identity		Open · Scan
M07588_2.00	NN 70-40%	CisBP	TCCTTCCCTCTTTCC	50.9% identity		Open · Scan
M07729_2.00	NN 70-40%	CisBP	CCAGACTGCCTGCCAAAACCCCCT	50.9% identity		Open · Scan
MA1597.1	NN 70-40%	JASPAR	CCCAGGGAAGCCATTTC	50.9% identity		Open · Scan
M00149_2.00	NN 70-40%	CisBP	CGTACGCC	50.8% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	50.8% identity		Open · Scan
M07600_2.00	NN 70-40%	CisBP	GCATTAGC	50.7% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	50.7% identity		Open · Scan
M07635_2.00	NN 70-40%	CisBP	AAGTTTTCTTGTATTATATCT	50.7% identity		Open · Scan
M07693_2.00	NN 70-40%	CisBP	CTCCTGTGTGTGCCTTGGCTG	50.7% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	50.7% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	50.4% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	50.4% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	50.3% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	50.2% identity		Open · Scan
M07764_2.00	NN 70-40%	CisBP	CTGCACTCTCCCCTTCCCCCCCTCCCC	50.2% identity		Open · Scan
M08335_2.00	NN 70-40%	CisBP	AGTCGTTGTCTG	50.2% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	50.2% identity		Open · Scan
M06179_2.00	NN 70-40%	CisBP	TAAGCCTATAGA	50.0% identity		Open · Scan

ModCRE6

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_tr_Q96JS8_Q96JS8_HUMAN:126:177_1llm_D_1	ModCRE	Homology model	TTCGCCCGCTGG	Region 126-177 · 1 3D model		Open · Scan
TFS_tr_Q96JS8_Q96JS8_HUMAN:25:178_2i13_A_1	ModCRE	Homology model	AAAAAACTTAACCAGCGTCAA	Region 25-178 · 1 3D model		Open · Scan
TFS_tr_Q96JS8_Q96JS8_HUMAN:3:207_5wjq_D_1	ModCRE	Homology model	AGCCGCACCCCGCCCCGCGCCCGTGCC	Region 3-207 · 1 3D model		Open · Scan
TFS_tr_Q96JS8_Q96JS8_HUMAN:41:151_5ei9_E_1	ModCRE	Homology model	GGCCCCCCCCCCCCCCG	Region 41-151 · 1 3D model		Open · Scan
TFS_tr_Q96JS8_Q96JS8_HUMAN:6:207_5v3j_E_1	ModCRE	Homology model	GGCTGGCCGCCCCCCCCCCGGGGGGG	Region 6-207 · 1 3D model		Open · Scan
TFS_tr_Q96JS8_Q96JS8_HUMAN:6:207_5v3m_C_1	ModCRE	Homology model	GGGCCCAGGGGGGCGGGGCCCCGCGC	Region 6-207 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 240 aa

3-207

Region 3-207 6 PWM

Residues

205 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

6 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

6 active PDB models 6 summary rows

Region 3-2076 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_Q96JS8_Q96JS8_HUMAN:126:177_1llm_D_1	1llm	126-177	View model · PDB
Predicted = Low	TFS_tr_Q96JS8_Q96JS8_HUMAN:25:178_2i13_A_1	2i13	25-178	View model · PDB
Predicted = Low	TFS_tr_Q96JS8_Q96JS8_HUMAN:3:207_5wjq_D_1	5wjq	3-207	View model · PDB
Predicted = Low	TFS_tr_Q96JS8_Q96JS8_HUMAN:41:151_5ei9_E_1	5ei9	41-151	View model · PDB
Predicted = Low	TFS_tr_Q96JS8_Q96JS8_HUMAN:6:207_5v3j_E_1	5v3j	6-207	View model · PDB
Predicted = Low	TFS_tr_Q96JS8_Q96JS8_HUMAN:6:207_5v3m_C_1	5v3m	6-207	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
5	5ei9	3:211	41	151	P:E · DNA:A,B	70.3% / 79.3%	100	View · PDB TFS_tr_Q96JS8_Q96JS8_HUMAN:41:151_5ei9_E_1
4	2i13	3:211	25	178	P:A · DNA:C,D	54.5% / 68.2%	100	View · PDB TFS_tr_Q96JS8_Q96JS8_HUMAN:25:178_2i13_A_1
2	5v3m	3:211	6	207	P:C · DNA:A,B	50.0% / 66.8%	72	View · PDB TFS_tr_Q96JS8_Q96JS8_HUMAN:6:207_5v3m_C_1
3	5v3j	3:211	6	207	P:E · DNA:A,B	50.0% / 66.8%	72	View · PDB TFS_tr_Q96JS8_Q96JS8_HUMAN:6:207_5v3j_E_1
1	5wjq	3:211	3	207	P:D · DNA:A,B	48.8% / 66.8%	72	View · PDB TFS_tr_Q96JS8_Q96JS8_HUMAN:3:207_5wjq_D_1
1	1llm	3:211	126,126	177,177	P:C,D · DNA:A,B	48.1% / 55.8%	59,61	View · PDB DIMER_tr_Q96JS8_Q96JS8_HUMAN:126:177_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
16-38	PF00096	Zinc finger, C2H2 type	overlaps 3-207
44-66	PF00096	Zinc finger, C2H2 type	overlaps 3-207
72-94	PF00096	Zinc finger, C2H2 type	overlaps 3-207
100-122	PF00096	Zinc finger, C2H2 type	overlaps 3-207
128-150	PF00096	Zinc finger, C2H2 type	overlaps 3-207
156-178	PF00096	Zinc finger, C2H2 type	overlaps 3-207
184-206	PF00096	Zinc finger, C2H2 type	overlaps 3-207