ModCRE DB

Transcription factor

Q96N77 - ZNF641

Zinc finger protein 641

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 438 aa

30 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M07615_2.00 Known CisBP ACCCCCCCA Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)24
MotifPredictionSourceDNA bindingSupportLogoActions
M00765_2.00 NN 70-40% CisBP CCCGCCCCC 57.4% identity Open · Scan
M01538_2.00 NN 70-40% CisBP GCCCCTGA 57.1% identity Open · Scan
M06135_2.00 NN 70-40% CisBP CAGCCACGCCCACCT 56.3% identity Open · Scan
M01440_2.00 NN 70-40% CisBP TACGCCAC 54.3% identity Open · Scan
M08540_2.00 NN 70-40% CisBP CCCCT 53.4% identity Open · Scan
M01441_2.00 NN 70-40% CisBP CCCCTGAATT 52.7% identity Open · Scan
M08525_2.00 NN 70-40% CisBP CCCCGCA 52.6% identity Open · Scan
M09002_2.00 NN 70-40% CisBP CCACCTGG 52.0% identity Open · Scan
MA1558.1 NN 70-40% JASPAR GGCAGGTGCA 52.0% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 51.8% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 51.8% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 51.8% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 51.8% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 51.8% identity Open · Scan
M01199_2.00 NN 70-40% CisBP GCGCCACC 50.9% identity Open · Scan
M01470_2.00 NN 70-40% CisBP CCCCCCGC 50.9% identity Open · Scan
M01529_2.00 NN 70-40% CisBP CCCCGCATT 50.9% identity Open · Scan
MA0748.1 NN 70-40% JASPAR GTCCGCCATTA 50.8% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 50.6% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 50.6% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 50.6% identity Open · Scan
M00031_2.00 NN 70-40% CisBP TACCCCGCAC 50.0% identity Open · Scan
M01180_2.00 NN 70-40% CisBP ACCCCTGG 50.0% identity Open · Scan
M02903_2.00 NN 70-40% CisBP ATGCCACGCCCCTTTTTG 50.0% identity Open · Scan
ModCRE5
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q96N77_ZN641_HUMAN:372:422_5yj3_C_1 ModCRE Homology model ACCCC Region 372-422 · 1 3D model Open · Scan
TFS_sp_Q96N77_ZN641_HUMAN:374:422_3uk3_C_1 ModCRE Homology model ATGGCTTGATT Region 374-422 · 1 3D model Open · Scan
TFS_sp_Q96N77_ZN641_HUMAN:374:422_3uk3_D_1 ModCRE Homology model AATCAACCCG Region 374-422 · 1 3D model Open · Scan
TFS_sp_Q96N77_ZN641_HUMAN:374:422_4is1_C_1 ModCRE Homology model ACGTCTGCATT Region 374-422 · 1 3D model Open · Scan
TFS_sp_Q96N77_ZN641_HUMAN:374:422_4is1_D_1 ModCRE Homology model TATTCAAACG Region 374-422 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 438 aa
262-422

Region 262-422 5 PWM

Residues
161 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
11 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 3UK3, 4IS1, 5EI9, 5V3J, 5V3M, 5WJQ, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 6 summary rows
Region 262-42211 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q96N77_ZN641_HUMAN:374:418_1llm_D_1 1llm 374-418 View model · PDB
Predicted = Low TFS_sp_Q96N77_ZN641_HUMAN:262:354_5ei9_E_1 5ei9 262-354 View model · PDB
Predicted = Low TFS_sp_Q96N77_ZN641_HUMAN:262:422_5v3j_E_1 5v3j 262-422 View model · PDB
Predicted = Low TFS_sp_Q96N77_ZN641_HUMAN:262:422_5v3m_C_1 5v3m 262-422 View model · PDB
Predicted = Low TFS_sp_Q96N77_ZN641_HUMAN:262:422_5wjq_D_1 5wjq 262-422 View model · PDB
Predicted = Low TFS_sp_Q96N77_ZN641_HUMAN:273:422_2i13_A_1 2i13 273-422 View model · PDB
Predicted = Low TFS_sp_Q96N77_ZN641_HUMAN:372:422_5yj3_C_1 5yj3 372-422 View model · PDB
Predicted = Low TFS_sp_Q96N77_ZN641_HUMAN:374:422_3uk3_C_1 3uk3 374-422 View model · PDB
Predicted = Low TFS_sp_Q96N77_ZN641_HUMAN:374:422_3uk3_D_1 3uk3 374-422 View model · PDB
Predicted = Low TFS_sp_Q96N77_ZN641_HUMAN:374:422_4is1_C_1 4is1 374-422 View model · PDB
Predicted = Low TFS_sp_Q96N77_ZN641_HUMAN:374:422_4is1_D_1 4is1 374-422 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 5ei9 261:427 262 354 P:E · DNA:A,B 48.4% / 64.5% 83 View · PDB TFS_sp_Q96N77_ZN641_HUMAN:262:354_5ei9_E_1
1 1llm 261:427 374,374 418,418 P:C,D · DNA:A,B 46.7% / 53.3% 51,52 View · PDB DIMER_sp_Q96N77_ZN641_HUMAN:374:418_1llm_D_1
1 5wjq 261:427 262 422 P:D · DNA:A,B 45.5% / 58.8% 57 View · PDB TFS_sp_Q96N77_ZN641_HUMAN:262:422_5wjq_D_1
2 2i13 261:427 273 422 P:A · DNA:C,D 44.2% / 56.5% 97 View · PDB TFS_sp_Q96N77_ZN641_HUMAN:273:422_2i13_A_1
3 5v3m 261:427 262 422 P:C · DNA:A,B 42.4% / 54.5% 58 View · PDB TFS_sp_Q96N77_ZN641_HUMAN:262:422_5v3m_C_1
4 5v3j 261:427 262 422 P:E · DNA:A,B 42.4% / 54.5% 58 View · PDB TFS_sp_Q96N77_ZN641_HUMAN:262:422_5v3j_E_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
108-149PF01352KRAB boxNo overlap with loaded model regions
264-286PF00096Zinc finger, C2H2 typeoverlaps 262-422
292-314PF00096Zinc finger, C2H2 typeoverlaps 262-422
321-342PF00096Zinc finger, C2H2 typeoverlaps 262-422
372-394PF00096Zinc finger, C2H2 typeoverlaps 262-422
400-422PF00096Zinc finger, C2H2 typeoverlaps 262-422