ModCRE DB

Transcription factor

Q96RK0 - CIC

Protein capicua homolog

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 2517 aa

7 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)1
MotifPredictionSourceDNA bindingSupportLogoActions
M03975_2.00 NN 70-40% CisBP TAACAATATCATTGTTA 53.2% identity Open · Scan
ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q96RK0_CIC_HUMAN:1107:1178_1o4x_B_1 ModCRE Homology model TTGCTTAATAGGGGCA Region 1107-1178 · 1 3D model Open · Scan
TFS_sp_Q96RK0_CIC_HUMAN:1107:1178_6ht5_D_1 ModCRE Homology model TTTCTTTAAAGGGGC Region 1107-1178 · 1 3D model Open · Scan
TFS_sp_Q96RK0_CIC_HUMAN:1107:1180_7m5w_A_1 ModCRE Homology model GATTTTGCTGAAAATGGT Region 1107-1180 · 1 3D model Open · Scan
TFS_sp_Q96RK0_CIC_HUMAN:1107:1185_1gt0_D_1 ModCRE Homology model TCTTTGTTGGGTCCT Region 1107-1185 · 1 3D model Open · Scan
TFS_sp_Q96RK0_CIC_HUMAN:1108:1176_2lef_A_1 ModCRE Homology model CCAGGAAAAAGGGGA Region 1108-1176 · 1 3D model Open · Scan
TFS_sp_Q96RK0_CIC_HUMAN:1108:1181_6jrp_A_1 ModCRE Homology model TTTTCATTAAA Region 1108-1181 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 2517 aa
1107-1185

Region 1107-1185 6 PWM

Residues
79 aa
Domains
PF00505 · HMG (high mobility group) box
3D models
6 active PDBs · 5 summary rows
Templates
1GT0, 1O4X, 2LEF, 6HT5, 6JRP, 7M5W
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 5 summary rows
Region 1107-11856 models · 5 summary rows
Actions
Predicted = Low TFS_sp_Q96RK0_CIC_HUMAN:1107:1178_1o4x_B_1 1o4x 1107-1178 View model · PDB
Predicted = Low TFS_sp_Q96RK0_CIC_HUMAN:1107:1178_6ht5_D_1 6ht5 1107-1178 View model · PDB
Predicted = Low TFS_sp_Q96RK0_CIC_HUMAN:1107:1180_7m5w_A_1 7m5w 1107-1180 View model · PDB
Predicted = Low TFS_sp_Q96RK0_CIC_HUMAN:1107:1185_1gt0_D_1 1gt0 1107-1185 View model · PDB
Predicted = Low TFS_sp_Q96RK0_CIC_HUMAN:1108:1176_2lef_A_1 2lef 1108-1176 View model · PDB
Predicted = Low TFS_sp_Q96RK0_CIC_HUMAN:1108:1181_6jrp_A_1 6jrp 1108-1181 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 6jrp 1103:1185 1108 1181 P:A · DNA:B,C 100.0% / 100.0% 100 View · PDB TFS_sp_Q96RK0_CIC_HUMAN:1108:1181_6jrp_A_1
2 7m5w 1103:1185 1107 1180 P:A · DNA:B,C 100.0% / 100.0% 53 View · PDB TFS_sp_Q96RK0_CIC_HUMAN:1107:1180_7m5w_A_1
5 6ht5 1103:1185 1107 1178 P:D · DNA:A,B 40.3% / 61.1% 93 View · PDB TFS_sp_Q96RK0_CIC_HUMAN:1107:1178_6ht5_D_1
4 1gt0 1103:1185 1107 1185 P:D · DNA:A,B 38.0% / 59.5% 100 View · PDB TFS_sp_Q96RK0_CIC_HUMAN:1107:1185_1gt0_D_1
3 2lef 1103:1185 1108 1176 P:A · DNA:B,C 36.2% / 66.7% 80 View · PDB TFS_sp_Q96RK0_CIC_HUMAN:1108:1176_2lef_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
251-347PF16090Protein capicua homolog-like domainNo overlap with loaded model regions
1110-1177PF00505HMG (high mobility group) boxoverlaps 1107-1185
2374-2428PF25981Protein capicua homolog-like, C-terminal tri-helical domainNo overlap with loaded model regions