Transcription factor

Q96T92 - INSM2

Insulinoma-associated protein 2 (Zinc finger protein IA-6)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 566 aa

9 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)3

Motif	Prediction	Source	DNA binding	Support	Actions
MA1548.1	NN 70-40%	JASPAR	TGGGCCCCCT	54.5% identity	Open · Scan
M02917_2.00	NN 70-40%	CisBP	GAACATCTGGATG	52.0% identity	Open · Scan
MA0698.1	NN 70-40%	JASPAR	CATCCAGATGTTC	52.0% identity	Open · Scan

ModCRE6

Motif	Prediction	Source	DNA binding	Support	Actions
DIMER_sp_Q96T92_INSM2_HUMAN:470:489_1llm_D_1	ModCRE	Homology model	TCCGCCGGCGGG	Region 470-489 · 1 3D model	Open · Scan
TFS_sp_Q96T92_INSM2_HUMAN:263:313_6e93_A_1	ModCRE	Homology model	GCCCCGGGGCCTA	Region 263-313 · 1 3D model	Open · Scan
TFS_sp_Q96T92_INSM2_HUMAN:263:313_6e94_A_1	ModCRE	Homology model	GGCTGCGGATCTA	Region 263-313 · 1 3D model	Open · Scan
TFS_sp_Q96T92_INSM2_HUMAN:265:313_2i13_A_1	ModCRE	Homology model	ATTTAACTCGAACCT	Region 265-313 · 1 3D model	Open · Scan
TFS_sp_Q96T92_INSM2_HUMAN:422:448_1g2f_C_1	ModCRE	Homology model	GAGGCCCGGGCCT	Region 422-448 · 1 3D model	Open · Scan
TFS_sp_Q96T92_INSM2_HUMAN:470:489_1llm_D_1	ModCRE	Homology model	TCCGCCGGCGGG	Region 470-489 · 1 3D model	Open · Scan

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 566 aa

263-313

422-448

470-489

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3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

6 active PDB models 6 summary rows

Region 263-3133 models · 3 summary rows

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	256:314	265	313	P:A · DNA:C,D	38.8% / 57.1%	32	View · PDB TFS_sp_Q96T92_INSM2_HUMAN:265:313_2i13_A_1
1	6e93	256:314	263	313	P:A · DNA:C,D	33.3% / 45.1%	45	View · PDB TFS_sp_Q96T92_INSM2_HUMAN:263:313_6e93_A_1
2	6e94	256:314	263	313	P:A · DNA:C,D	33.3% / 45.1%	45	View · PDB TFS_sp_Q96T92_INSM2_HUMAN:263:313_6e94_A_1

Region 422-4481 model · 1 summary row

				Actions
Predicted = Low	TFS_sp_Q96T92_INSM2_HUMAN:422:448_1g2f_C_1	1g2f	422-448	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
5	1g2f	256:314	422	448	P:C · DNA:A,B	40.7% / 55.6%	30	View · PDB TFS_sp_Q96T92_INSM2_HUMAN:422:448_1g2f_C_1

Region 470-4892 models · 2 summary rows

				Actions
Predicted = Low	DIMER_sp_Q96T92_INSM2_HUMAN:470:489_1llm_D_1	1llm	470-489	View model · PDB
Predicted = Low	TFS_sp_Q96T92_INSM2_HUMAN:470:489_1llm_D_1	1llm	470-489	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
1	1llm	256:314	470,470	489,489	P:C,D · DNA:A,B	50.0% / 70.0%	22,23	View · PDB DIMER_sp_Q96T92_INSM2_HUMAN:470:489_1llm_D_1
3	1llm	256:314	470,470	489,489	P:C,D · DNA:A,B	50.0% / 70.0%	22,23	View · PDB TFS_sp_Q96T92_INSM2_HUMAN:470:489_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
291-313	PF00096	Zinc finger, C2H2 type	overlaps 263-313
426-448	PF00096	Zinc finger, C2H2 type	overlaps 422-448