Transcription factor

Q99676 - ZNF184

Zinc finger protein 184

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 751 aa

86 Generated PWM 7 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known3

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
MA2120.1	Known	JASPAR	TAGAAAGGTGCAT	Direct PWM		Open · Scan
M07571_2.00	Known	CisBP	CCCTTTGCTATGATGCACCTTTCTAAT	Direct PWM		Open · Scan
M08285_2.00	Known	CisBP	TCCTCACCA	Direct PWM		Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)77

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	67.8% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	67.0% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	67.0% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	66.6% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	65.8% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	65.8% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	65.4% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	65.4% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	64.7% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	64.7% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	64.7% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	64.7% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	64.5% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	64.2% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	63.0% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	62.0% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	61.9% identity		Open · Scan
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	61.9% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	59.6% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	59.3% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	59.2% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	59.1% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	58.8% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	58.0% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	57.5% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	57.5% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	57.2% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	57.2% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	57.2% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	56.5% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	56.2% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	55.8% identity		Open · Scan
M07684_2.00	NN 70-40%	CisBP	CCTGTTCTTGACTTT	55.8% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	55.7% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	55.6% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	55.6% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	55.1% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	55.0% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	54.7% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	54.5% identity		Open · Scan
M07747_2.00	NN 70-40%	CisBP	TGGTCTATAAAGGGCCTGGTT	54.3% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	54.3% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	53.6% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	53.3% identity		Open · Scan
M07727_2.00	NN 70-40%	CisBP	CGCCGCCTCCCC	53.0% identity		Open · Scan
MA1596.1	NN 70-40%	JASPAR	GCCTCAGCCTCCCGAG	53.0% identity		Open · Scan
M01474_2.00	NN 70-40%	CisBP	CGCCGATCAC	52.9% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	52.4% identity		Open · Scan
M01538_2.00	NN 70-40%	CisBP	GCCCCTGA	52.2% identity		Open · Scan
MA1154.1	NN 70-40%	JASPAR	CTTTCCCACAACACGAC	52.1% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	51.8% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	51.8% identity		Open · Scan
M06179_2.00	NN 70-40%	CisBP	TAAGCCTATAGA	51.8% identity		Open · Scan
M08859_2.00	NN 70-40%	CisBP	CATTTTTTCCTCCTAGGCCT	51.8% identity		Open · Scan
M01039_2.00	NN 70-40%	CisBP	CCCCCTA	51.7% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	51.6% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	51.6% identity		Open · Scan
M07635_2.00	NN 70-40%	CisBP	AAGTTTTCTTGTATTATATCT	51.5% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	51.5% identity		Open · Scan
M08366_2.00	NN 70-40%	CisBP	GTTTGCTGCTTACAA	51.3% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	51.2% identity		Open · Scan
M08314_2.00	NN 70-40%	CisBP	ATTCATCAAGGTCCTCAACAATGG	51.1% identity		Open · Scan
M08283_2.00	NN 70-40%	CisBP	GACTTTTATTTT	51.0% identity		Open · Scan
MA0130.1	NN 70-40%	JASPAR	ATCCAC	51.0% identity		Open · Scan
M03710_2.00	NN 70-40%	CisBP	CTCACGCCCCCC	50.6% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	50.6% identity		Open · Scan
MA0528.1	NN 70-40%	JASPAR	GGAGGAGGAGGGGGAGGAGGA	50.4% identity		Open · Scan
M07590_2.00	NN 70-40%	CisBP	TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT	50.3% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	50.1% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	50.1% identity		Open · Scan
M07702_2.00	NN 70-40%	CisBP	CTTCTTCCTTGG	50.1% identity		Open · Scan
M08247_2.00	NN 70-40%	CisBP	AAAAATAACAAACGG	50.1% identity		Open · Scan
M01883_2.00	NN 70-40%	CisBP	TGCCCCTGA	50.0% identity		Open · Scan
M03671_2.00	NN 70-40%	CisBP	ATTACCATACAAGTGCAC	50.0% identity		Open · Scan
M03702_2.00	NN 70-40%	CisBP	GACCCCCCACGACGC	50.0% identity		Open · Scan
M08256_2.00	NN 70-40%	CisBP	GTGCCTT	50.0% identity		Open · Scan
MA0750.1	NN 70-40%	JASPAR	GGCGACCACCGA	50.0% identity		Open · Scan

ModCRE6

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_sp_Q99676_ZN184_HUMAN:640:690_1llm_C_1	ModCRE	Homology model	CCCCGCGCGCGG	Region 640-690 · 1 3D model		Open · Scan
TFS_sp_Q99676_ZN184_HUMAN:247:357_5ei9_E_1	ModCRE	Homology model	CCGGGGAAGGGCGGGGA	Region 247-357 · 1 3D model		Open · Scan
TFS_sp_Q99676_ZN184_HUMAN:259:412_2i13_A_1	ModCRE	Homology model	GCTATTATACTAAGAAGCCAA	Region 259-412 · 1 3D model		Open · Scan
TFS_sp_Q99676_ZN184_HUMAN:305:581_5v3j_E_1	ModCRE	Homology model	CCCTCGGTTCCCGGTTCCCCAAACCG	Region 305-581 · 1 3D model		Open · Scan
TFS_sp_Q99676_ZN184_HUMAN:305:581_5v3m_C_1	ModCRE	Homology model	GGCCCCCGCCGCCCCCGACGCAAGGC	Region 305-581 · 1 3D model		Open · Scan
TFS_sp_Q99676_ZN184_HUMAN:331:609_5wjq_D_1	ModCRE	Homology model	CCAATCCGCGCGCCCCCGGGGGCCCGCA	Region 331-609 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 751 aa

247-690

Region 247-690 6 PWM

Residues

444 aa

Domains

PF00096 · Zinc finger, C2H2 type PF13465 · Zinc-finger double domain PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

7 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

7 active PDB models 6 summary rows

Region 247-6907 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_Q99676_ZN184_HUMAN:640:690_1llm_C_1	1llm	640-690	View model · PDB
Predicted = Low	TFS_sp_Q99676_ZN184_HUMAN:247:357_5ei9_E_1	5ei9	247-357	View model · PDB
Predicted = Low	TFS_sp_Q99676_ZN184_HUMAN:259:412_2i13_A_1	2i13	259-412	View model · PDB
Predicted = Low	TFS_sp_Q99676_ZN184_HUMAN:305:581_5v3j_E_1	5v3j	305-581	View model · PDB
Predicted = Low	TFS_sp_Q99676_ZN184_HUMAN:305:581_5v3m_C_1	5v3m	305-581	View model · PDB
Predicted = Low	TFS_sp_Q99676_ZN184_HUMAN:331:609_5wjq_D_1	5wjq	331-609	View model · PDB
Predicted = Low	TFS_sp_Q99676_ZN184_HUMAN:362:660_7w1m_H_1	7w1m	362-660	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	223:746	259	412	P:A · DNA:C,D	60.4% / 70.8%	100	View · PDB TFS_sp_Q99676_ZN184_HUMAN:259:412_2i13_A_1
1	5wjq	223:746	331	609	P:D · DNA:A,B	55.2% / 69.5%	99	View · PDB TFS_sp_Q99676_ZN184_HUMAN:331:609_5wjq_D_1
2	5v3m	223:746	305	581	P:C · DNA:A,B	54.2% / 68.2%	100	View · PDB TFS_sp_Q99676_ZN184_HUMAN:305:581_5v3m_C_1
3	5v3j	223:746	305	581	P:E · DNA:A,B	54.2% / 68.2%	100	View · PDB TFS_sp_Q99676_ZN184_HUMAN:305:581_5v3j_E_1
1	1llm	223:746	640,640	690,690	P:C,D · DNA:A,B	49.0% / 66.7%	58,60	View · PDB DIMER_sp_Q99676_ZN184_HUMAN:640:690_1llm_C_1
5	7w1m	223:746	362	660	P:H · DNA:F,G	35.4% / 52.9%	92	View · PDB TFS_sp_Q99676_ZN184_HUMAN:362:660_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
28-68	PF01352	KRAB box	No overlap with loaded model regions
222-244	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
250-272	PF00096	Zinc finger, C2H2 type	overlaps 247-690
292-317	PF13465	Zinc-finger double domain	overlaps 247-690
334-356	PF00096	Zinc finger, C2H2 type	overlaps 247-690
362-384	PF00096	Zinc finger, C2H2 type	overlaps 247-690
390-412	PF00096	Zinc finger, C2H2 type	overlaps 247-690
418-440	PF00096	Zinc finger, C2H2 type	overlaps 247-690
446-468	PF00096	Zinc finger, C2H2 type	overlaps 247-690
474-496	PF00096	Zinc finger, C2H2 type	overlaps 247-690
502-524	PF00096	Zinc finger, C2H2 type	overlaps 247-690
530-552	PF00096	Zinc finger, C2H2 type	overlaps 247-690
558-580	PF00096	Zinc finger, C2H2 type	overlaps 247-690
586-608	PF00096	Zinc finger, C2H2 type	overlaps 247-690
614-636	PF00096	Zinc finger, C2H2 type	overlaps 247-690
642-664	PF00096	Zinc finger, C2H2 type	overlaps 247-690
670-692	PF00096	Zinc finger, C2H2 type	overlaps 247-690
698-720	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
728-748	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions