ModCRE DB

Transcription factor

Q99697 - PITX2

Pituitary homeobox 2 (ALL1-responsive protein ARP1) (Homeobox protein PITX2) (Paired-like homeodomain transcription factor 2) (RIEG bicoid-related homeobox transcription factor) (Solurshin)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 317 aa

11 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known11
MotifPredictionSourceDNA bindingSupportLogoActions
MA1547.1 Known JASPAR ATAATCCC Direct PWM Open · Scan
MA1547.2 Known JASPAR TTAATCCC Direct PWM Open · Scan
M00310_2.00 Known CisBP TTAATCCC Direct PWM Open · Scan
M00311_2.00 Known CisBP TTAATCCC Direct PWM Open · Scan
M00312_2.00 Known CisBP AGGTATTAATTAA Direct PWM Open · Scan
M00313_2.00 Known CisBP TTAATCCC Direct PWM Open · Scan
M00314_2.00 Known CisBP TTAATCCC Direct PWM Open · Scan
M05229_2.00 Known CisBP CTAATCCC Direct PWM Open · Scan
M05230_2.00 Known CisBP CTAATCCC Direct PWM Open · Scan
M05231_2.00 Known CisBP ATAATCCC Direct PWM Open · Scan
M05232_2.00 Known CisBP CTAATCCC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 317 aa
84-143

Region 84-143 0 PWM

Residues
60 aa
Domains
PF00046 · Homeodomain
3D models
1 active PDB
Templates
1FJL
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 84-1431 model
Actions
Predicted = Low DIMER_Q99697:84:143_1fjl_A_1 1fjl 84-143 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
86-142PF00046Homeodomainoverlaps 84-143
275-292PF03826OAR motifNo overlap with loaded model regions