ModCRE DB

Transcription factor

Q99742 - NPAS1

Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Basic-helix-loop-helix-PAS protein MOP5) (Class E basic helix-loop-helix protein 11) (bHLHe11) (Member of PAS protein 5) (PAS domain-containing protein 5)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 590 aa

8 Generated PWM 8 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE8
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q99742_NPAS1_HUMAN:142:198_8osl_N_1 ModCRE Homology model CACATGGTGCGCATAT Region 142-198 · 1 3D model Open · Scan
DIMER_sp_Q99742_NPAS1_HUMAN:45:406_4zpr_B_1 ModCRE Homology model GCGCGTACGCGCCGGGG Region 45-406 · 1 3D model Open · Scan
DIMER_sp_Q99742_NPAS1_HUMAN:46:407_4zpk_B_1 ModCRE Homology model CCCCACACGTGCCCC Region 46-407 · 1 3D model Open · Scan
DIMER_sp_Q99742_NPAS1_HUMAN:46:420_5sy7_B_1 ModCRE Homology model GCGCGCACGTGCGGGGGG Region 46-420 · 1 3D model Open · Scan
TFS_sp_Q99742_NPAS1_HUMAN:142:198_8osl_N_1 ModCRE Homology model ATATGCGCACCATGTG Region 142-198 · 1 3D model Open · Scan
TFS_sp_Q99742_NPAS1_HUMAN:45:406_4zpr_B_1 ModCRE Homology model GCGCGTACGCGCCGGGC Region 45-406 · 1 3D model Open · Scan
TFS_sp_Q99742_NPAS1_HUMAN:46:407_4zpk_B_1 ModCRE Homology model CCCCACACGTGCCCC Region 46-407 · 1 3D model Open · Scan
TFS_sp_Q99742_NPAS1_HUMAN:46:420_5sy7_B_1 ModCRE Homology model ACGCGCACGTGCGGGGGG Region 46-420 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 590 aa
45-420

Region 45-420 8 PWM

Residues
376 aa
Domains
PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain PF00989 · PAS fold PF08447 · PAS fold
3D models
8 active PDBs · 8 summary rows
Templates
4ZPK, 4ZPR, 5SY7, 8OSL
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
8 active PDB models 8 summary rows
Region 45-4208 models · 8 summary rows
Actions
Predicted = Low DIMER_sp_Q99742_NPAS1_HUMAN:142:198_8osl_N_1 8osl 142-198 View model · PDB
Predicted = Low DIMER_sp_Q99742_NPAS1_HUMAN:45:406_4zpr_B_1 4zpr 45-406 View model · PDB
Predicted = Low DIMER_sp_Q99742_NPAS1_HUMAN:46:407_4zpk_B_1 4zpk 46-407 View model · PDB
Predicted = Low DIMER_sp_Q99742_NPAS1_HUMAN:46:420_5sy7_B_1 5sy7 46-420 View model · PDB
Predicted = Low TFS_sp_Q99742_NPAS1_HUMAN:142:198_8osl_N_1 8osl 142-198 View model · PDB
Predicted = Low TFS_sp_Q99742_NPAS1_HUMAN:45:406_4zpr_B_1 4zpr 45-406 View model · PDB
Predicted = Low TFS_sp_Q99742_NPAS1_HUMAN:46:407_4zpk_B_1 4zpk 46-407 View model · PDB
Predicted = Low TFS_sp_Q99742_NPAS1_HUMAN:46:420_5sy7_B_1 5sy7 46-420 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5sy7 45:420 135,46 198,420 P:A,B · DNA:C,D 48.1% / 59.5% 23,99 View · PDB TFS_sp_Q99742_NPAS1_HUMAN:46:420_5sy7_B_1
1 5sy7 45:420 135,46 198,420 P:A,B · DNA:C,D 48.1% / 59.5% 23,99 View · PDB DIMER_sp_Q99742_NPAS1_HUMAN:46:420_5sy7_B_1
4 8osl 45:420 142,47 198,95 P:N,P · DNA:I,J 46.6% / 69.0% 19,98 View · PDB TFS_sp_Q99742_NPAS1_HUMAN:142:198_8osl_N_1
4 8osl 45:420 142,47 198,95 P:N,P · DNA:I,J 46.6% / 69.0% 19,98 View · PDB DIMER_sp_Q99742_NPAS1_HUMAN:142:198_8osl_N_1
3 4zpr 45:420 135,45 198,406 P:A,B · DNA:C,D 30.7% / 47.8% 26,97 View · PDB TFS_sp_Q99742_NPAS1_HUMAN:45:406_4zpr_B_1
3 4zpr 45:420 135,45 198,406 P:A,B · DNA:C,D 30.7% / 47.8% 26,97 View · PDB DIMER_sp_Q99742_NPAS1_HUMAN:45:406_4zpr_B_1
2 4zpk 45:420 135,46 198,407 P:A,B · DNA:C,D 29.8% / 47.8% 23,93 View · PDB TFS_sp_Q99742_NPAS1_HUMAN:46:407_4zpk_B_1
2 4zpk 45:420 135,46 198,407 P:A,B · DNA:C,D 29.8% / 47.8% 23,93 View · PDB DIMER_sp_Q99742_NPAS1_HUMAN:46:407_4zpk_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
45-102PF23171Hypoxia-inducible factor 1-alpha bHLH domainoverlaps 45-420
141-198PF00989PAS foldoverlaps 45-420
316-392PF08447PAS foldoverlaps 45-420