Region 16-66 0 PWM
- Residues
- 51 aa
- Domains
- PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain
- 3D models
- 1 active PDB
- Templates
- 4H10
- Sources
- Structure model
Transcription factor
Q99814 - EPAS1
Endothelial PAS domain-containing protein 1 (EPAS-1) (Basic-helix-loop-helix-PAS protein MOP2) (Class E basic helix-loop-helix protein 73) (bHLHe73) (HIF-1-alpha-like factor) (HLF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha) (Member of PAS protein 2) (PAS domain-containing protein 2)
Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 870 aa
Motif Prediction
Only entries with a generated matrix are shown here.
Known4
| Motif | Prediction | Source | DNA binding | Support | Logo | Actions |
|---|---|---|---|---|---|---|
| M09455_2.00 | Known | CisBP | GCACGTACCC | Direct PWM | Open · Scan | |
| MA2325.1 | Known | JASPAR | CGCACGTAC | Direct PWM | Open · Scan | |
| M08719_2.00 | Known | CisBP | GTACGTGCC | Direct PWM | Open · Scan | |
| EPAS1_HUMAN.H11MO.0.B | Known | HOCOMOCO | GTACGTGCC | Direct PWM | Open · Scan |
Nearest Neighbor (>70%)0
No generated PWM in this category.
Nearest Neighbor (70% - 40%)0
No generated PWM in this category.
ModCRE0
No generated PWM in this category.
Model-supported DNA-binding regions
Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.
1
870 aa
16-66
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
Region 16-661 model
| Actions | ||||
|---|---|---|---|---|
| Predicted = Low | DIMER_Q99814:16:66_4h10_A_1 | 4h10 | 16-66 | View model · PDB |
View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.
Domains
Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.
| Residues | PFAM | Domain | Used by prediction region? |
|---|---|---|---|
| 5-70 | PF23171 | Hypoxia-inducible factor 1-alpha bHLH domain | overlaps 16-66 |
| 93-162 | PF00989 | PAS fold | No overlap with loaded model regions |
| 243-347 | PF14598 | PAS domain | No overlap with loaded model regions |
| 517-549 | PF11413 | Hypoxia-inducible factor-1 | No overlap with loaded model regions |
| 833-869 | PF08778 | HIF-1 alpha C terminal transactivation domain | No overlap with loaded model regions |