ModCRE DB

Transcription factor

Q9BS31 - ZNF649

Zinc finger protein 649

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 505 aa

54 Generated PWM 7 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M07738_2.00 Known CisBP TTATAT Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)48
MotifPredictionSourceDNA bindingSupportLogoActions
M00952_2.00 NN 70-40% CisBP GGATGCTC 65.8% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 65.8% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 64.7% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 64.7% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 64.7% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 64.7% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 62.3% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 62.3% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 62.3% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 60.0% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 57.9% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 57.6% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 57.3% identity Open · Scan
M07646_2.00 NN 70-40% CisBP CTTTTTTTT 56.9% identity Open · Scan
M07725_2.00 NN 70-40% CisBP AAGCACTGTACT 56.7% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 56.4% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 55.8% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 55.8% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 55.0% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 55.0% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 54.7% identity Open · Scan
M08292_2.00 NN 70-40% CisBP TGTATTCCTTGTCATGTGTGG 54.3% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 54.3% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 54.1% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 54.0% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 53.9% identity Open · Scan
M08949_2.00 NN 70-40% CisBP TTCTATTTCTTCTTGTGTCA 53.5% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 53.4% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 53.2% identity Open · Scan
M08255_2.00 NN 70-40% CisBP CTCTTCCGGT 53.1% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 53.0% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 52.7% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 52.7% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 52.4% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 52.1% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 51.7% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 51.7% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 51.7% identity Open · Scan
M06084_2.00 NN 70-40% CisBP AGACCACCCAC 51.6% identity Open · Scan
M07777_2.00 NN 70-40% CisBP GCCAATTTCCGTGGTGTAAAT 51.5% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 51.3% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 51.2% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 51.0% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 51.0% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 50.6% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 50.5% identity Open · Scan
M08300_2.00 NN 70-40% CisBP CTGCCCAATTCAT 50.1% identity Open · Scan
M08392_2.00 NN 70-40% CisBP CTTCACCTGCTGAGG 50.1% identity Open · Scan
ModCRE5
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q9BS31_ZN649_HUMAN:175:453_5wjq_D_1 ModCRE Homology model CGGCGCGGCCCCCCCGCCCCTGAGTCCC Region 175-453 · 1 3D model Open · Scan
TFS_sp_Q9BS31_ZN649_HUMAN:178:453_5v3j_E_1 ModCRE Homology model CCGGGATCCTTCGGCCATCCCGAGCG Region 178-453 · 1 3D model Open · Scan
TFS_sp_Q9BS31_ZN649_HUMAN:178:453_5v3m_C_1 ModCRE Homology model CACCCACGGGTCCCCCGTGCCGCGCC Region 178-453 · 1 3D model Open · Scan
TFS_sp_Q9BS31_ZN649_HUMAN:259:369_5ei9_E_1 ModCRE Homology model CCCCGGAGGGGGGGGCC Region 259-369 · 1 3D model Open · Scan
TFS_sp_Q9BS31_ZN649_HUMAN:271:424_2i13_A_1 ModCRE Homology model GGGCTGAGGGAGTCTCTAAGT Region 271-424 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 505 aa
175-453

Region 175-453 5 PWM

Residues
279 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
7 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
7 active PDB models 6 summary rows
Region 175-4537 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q9BS31_ZN649_HUMAN:287:337_1llm_D_1 1llm 287-337 View model · PDB
Predicted = Low TFS_sp_Q9BS31_ZN649_HUMAN:175:453_5wjq_D_1 5wjq 175-453 View model · PDB
Predicted = Low TFS_sp_Q9BS31_ZN649_HUMAN:178:453_5v3j_E_1 5v3j 178-453 View model · PDB
Predicted = Low TFS_sp_Q9BS31_ZN649_HUMAN:178:453_5v3m_C_1 5v3m 178-453 View model · PDB
Predicted = Low TFS_sp_Q9BS31_ZN649_HUMAN:179:452_7w1m_H_1 7w1m 179-452 View model · PDB
Predicted = Low TFS_sp_Q9BS31_ZN649_HUMAN:259:369_5ei9_E_1 5ei9 259-369 View model · PDB
Predicted = Low TFS_sp_Q9BS31_ZN649_HUMAN:271:424_2i13_A_1 2i13 271-424 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 161:460 271 424 P:A · DNA:C,D 59.1% / 71.4% 100 View · PDB TFS_sp_Q9BS31_ZN649_HUMAN:271:424_2i13_A_1
1 5v3m 161:460 178 453 P:C · DNA:A,B 47.8% / 65.2% 99 View · PDB TFS_sp_Q9BS31_ZN649_HUMAN:178:453_5v3m_C_1
2 5v3j 161:460 178 453 P:E · DNA:A,B 47.8% / 65.2% 99 View · PDB TFS_sp_Q9BS31_ZN649_HUMAN:178:453_5v3j_E_1
1 1llm 161:460 287,287 337,337 P:C,D · DNA:A,B 47.1% / 54.9% 58,60 View · PDB DIMER_sp_Q9BS31_ZN649_HUMAN:287:337_1llm_D_1
3 5wjq 161:460 175 453 P:D · DNA:A,B 47.0% / 62.4% 99 View · PDB TFS_sp_Q9BS31_ZN649_HUMAN:175:453_5wjq_D_1
5 7w1m 161:460 179 452 P:H · DNA:F,G 37.1% / 47.9% 85 View · PDB TFS_sp_Q9BS31_ZN649_HUMAN:179:452_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
7-48PF01352KRAB boxNo overlap with loaded model regions
178-200PF00096Zinc finger, C2H2 typeoverlaps 175-453
206-228PF00096Zinc finger, C2H2 typeoverlaps 175-453
264-284PF00096Zinc finger, C2H2 typeoverlaps 175-453
290-312PF00096Zinc finger, C2H2 typeoverlaps 175-453
318-340PF00096Zinc finger, C2H2 typeoverlaps 175-453
350-368PF00096Zinc finger, C2H2 typeoverlaps 175-453
374-396PF00096Zinc finger, C2H2 typeoverlaps 175-453
402-424PF00096Zinc finger, C2H2 typeoverlaps 175-453