ModCRE DB

Transcription factor

Q9GZX5 - ZNF350

Zinc finger protein 350 (KRAB zinc finger protein ZFQR) (Zinc finger and BRCA1-interacting protein with a KRAB domain 1) (Zinc finger protein ZBRK1)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 532 aa

77 Generated PWM 9 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known3
MotifPredictionSourceDNA bindingSupportLogoActions
M08396_2.00 Known CisBP CAGCTCTTTTATGACCAACCC Direct PWM Open · Scan
M08960_2.00 Known CisBP CAGTCCTTTTATGACCTA Direct PWM Open · Scan
ZN350_HUMAN.H11MO.0.C Known HOCOMOCO CAGTCCTTTTATGACCTA Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)65
MotifPredictionSourceDNA bindingSupportLogoActions
M00953_2.00 NN 70-40% CisBP ATCTATAT 67.0% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 65.8% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 64.7% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 64.7% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 63.5% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 63.5% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 63.5% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 63.5% identity Open · Scan
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 62.5% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 61.9% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 60.6% identity Open · Scan
M07725_2.00 NN 70-40% CisBP AAGCACTGTACT 59.8% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 59.6% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 59.2% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 59.2% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 59.2% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 58.9% identity Open · Scan
M08392_2.00 NN 70-40% CisBP CTTCACCTGCTGAGG 58.9% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 58.8% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 58.7% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 58.4% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 57.9% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 57.8% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 57.7% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 57.6% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 57.5% identity Open · Scan
M08949_2.00 NN 70-40% CisBP TTCTATTTCTTCTTGTGTCA 57.5% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 57.2% identity Open · Scan
M07678_2.00 NN 70-40% CisBP CCCGCCCCCTCCTCCCCCTTCCCACCC 56.2% identity Open · Scan
M07646_2.00 NN 70-40% CisBP CTTTTTTTT 56.0% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 55.9% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 55.6% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 55.5% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 55.4% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 55.4% identity Open · Scan
M07777_2.00 NN 70-40% CisBP GCCAATTTCCGTGGTGTAAAT 54.9% identity Open · Scan
M07660_2.00 NN 70-40% CisBP CCGCGCCTACCTGAGGGCGCGGGCCTGGGG 54.5% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 54.3% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 54.0% identity Open · Scan
M07588_2.00 NN 70-40% CisBP TCCTTCCCTCTTTCC 53.6% identity Open · Scan
M07754_2.00 NN 70-40% CisBP CGCCCCCTCCCT 53.5% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 53.2% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 52.8% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 52.7% identity Open · Scan
M08357_2.00 NN 70-40% CisBP GAGCCTGCTACTGAGCCTGGG 52.4% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 52.0% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 52.0% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 51.5% identity Open · Scan
M08314_2.00 NN 70-40% CisBP ATTCATCAAGGTCCTCAACAATGG 51.5% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 51.4% identity Open · Scan
M07648_2.00 NN 70-40% CisBP GCTTGCAAAAAAAATTTAACTCCCAGCTC 51.3% identity Open · Scan
M07657_2.00 NN 70-40% CisBP CCCCTGCATGTCCCCATTTTT 51.3% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 51.2% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 51.2% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 51.0% identity Open · Scan
M07593_2.00 NN 70-40% CisBP AGATGAAGTCACCCCTCTTAC 51.0% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 50.8% identity Open · Scan
MA0056.1 NN 70-40% JASPAR TGGGGA 50.6% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 50.6% identity Open · Scan
M07746_2.00 NN 70-40% CisBP CAGCTGGCGCCCAACATGGGTCCC 50.5% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 50.3% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 50.3% identity Open · Scan
M00645_2.00 NN 70-40% CisBP CGCCCACGCA 50.0% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 50.0% identity Open · Scan
M05844_2.00 NN 70-40% CisBP TCACCTGT 50.0% identity Open · Scan
ModCRE9
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q9GZX5_ZN350_HUMAN:232:281_1llm_D_1 ModCRE Homology model CCCCGCGCCGGG Region 232-281 · 1 3D model Open · Scan
TFS_sp_Q9GZX5_ZN350_HUMAN:196:425_5v3j_E_1 ModCRE Homology model CACCCGGGACCCCCACATGGGGGGCC Region 196-425 · 1 3D model Open · Scan
TFS_sp_Q9GZX5_ZN350_HUMAN:196:425_5v3m_C_1 ModCRE Homology model GGGGGGGGCCCACAGCTGGGGGCGCC Region 196-425 · 1 3D model Open · Scan
TFS_sp_Q9GZX5_ZN350_HUMAN:196:428_5wjq_D_1 ModCRE Homology model GGGCGGGGTCCGGGGGGGGGGCGCCCC Region 196-428 · 1 3D model Open · Scan
TFS_sp_Q9GZX5_ZN350_HUMAN:243:396_2i13_A_1 ModCRE Homology model GAGGCGCAGCTGGCTTTCAAT Region 243-396 · 1 3D model Open · Scan
TFS_sp_Q9GZX5_ZN350_HUMAN:259:369_5egb_A_1 ModCRE Homology model TTCTGGGGAAGGGGTGGG Region 259-369 · 1 3D model Open · Scan
TFS_sp_Q9GZX5_ZN350_HUMAN:259:369_5ei9_E_1 ModCRE Homology model GCCCTGGGGGAGGAGGGT Region 259-369 · 1 3D model Open · Scan
TFS_sp_Q9GZX5_ZN350_HUMAN:261:369_5eh2_F_1 ModCRE Homology model CCCCCGGGGACCCGGGCTG Region 261-369 · 1 3D model Open · Scan
TFS_sp_Q9GZX5_ZN350_HUMAN:317:427_6e93_A_1 ModCRE Homology model CCGGCGCTGACACAGTTG Region 317-427 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 532 aa
196-428

Region 196-428 9 PWM

Residues
233 aa
Domains
PF00096 · Zinc finger, C2H2 type PF13465 · Zinc-finger double domain PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
9 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EGB, 5EH2, 5EI9, 5V3J, 5V3M, 5WJQ, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
9 active PDB models 6 summary rows
Region 196-4289 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q9GZX5_ZN350_HUMAN:232:281_1llm_D_1 1llm 232-281 View model · PDB
Predicted = Low TFS_sp_Q9GZX5_ZN350_HUMAN:196:425_5v3j_E_1 5v3j 196-425 View model · PDB
Predicted = Low TFS_sp_Q9GZX5_ZN350_HUMAN:196:425_5v3m_C_1 5v3m 196-425 View model · PDB
Predicted = Low TFS_sp_Q9GZX5_ZN350_HUMAN:196:428_5wjq_D_1 5wjq 196-428 View model · PDB
Predicted = Low TFS_sp_Q9GZX5_ZN350_HUMAN:243:396_2i13_A_1 2i13 243-396 View model · PDB
Predicted = Low TFS_sp_Q9GZX5_ZN350_HUMAN:259:369_5egb_A_1 5egb 259-369 View model · PDB
Predicted = Low TFS_sp_Q9GZX5_ZN350_HUMAN:259:369_5ei9_E_1 5ei9 259-369 View model · PDB
Predicted = Low TFS_sp_Q9GZX5_ZN350_HUMAN:261:369_5eh2_F_1 5eh2 261-369 View model · PDB
Predicted = Low TFS_sp_Q9GZX5_ZN350_HUMAN:317:427_6e93_A_1 6e93 317-427 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 195:431 243 396 P:A · DNA:C,D 63.6% / 71.4% 100 View · PDB TFS_sp_Q9GZX5_ZN350_HUMAN:243:396_2i13_A_1
5 5ei9 195:431 259 369 P:E · DNA:A,B 62.2% / 76.6% 100 View · PDB TFS_sp_Q9GZX5_ZN350_HUMAN:259:369_5ei9_E_1
2 5v3m 195:431 196 425 P:C · DNA:A,B 50.4% / 67.0% 83 View · PDB TFS_sp_Q9GZX5_ZN350_HUMAN:196:425_5v3m_C_1
3 5v3j 195:431 196 425 P:E · DNA:A,B 50.4% / 67.0% 83 View · PDB TFS_sp_Q9GZX5_ZN350_HUMAN:196:425_5v3j_E_1
1 5wjq 195:431 196 428 P:D · DNA:A,B 50.2% / 66.5% 82 View · PDB TFS_sp_Q9GZX5_ZN350_HUMAN:196:428_5wjq_D_1
1 1llm 195:431 232,232 281,281 P:C,D · DNA:A,B 46.0% / 60.0% 57,58 View · PDB DIMER_sp_Q9GZX5_ZN350_HUMAN:232:281_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
7-48PF01352KRAB boxNo overlap with loaded model regions
206-228PF00096Zinc finger, C2H2 typeoverlaps 196-428
248-271PF13465Zinc-finger double domainoverlaps 196-428
290-312PF00096Zinc finger, C2H2 typeoverlaps 196-428
318-340PF00096Zinc finger, C2H2 typeoverlaps 196-428
346-368PF00096Zinc finger, C2H2 typeoverlaps 196-428
374-396PF00096Zinc finger, C2H2 typeoverlaps 196-428
404-424PF00096Zinc finger, C2H2 typeoverlaps 196-428