ModCRE DB

Transcription factor

Q9H116 - GZF1

GDNF-inducible zinc finger protein 1 (Zinc finger and BTB domain-containing protein 23) (Zinc finger protein 336)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 711 aa

21 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)15
MotifPredictionSourceDNA bindingSupportLogoActions
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 56.0% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 54.1% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 52.9% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 52.9% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 51.7% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 51.7% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 51.7% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 51.3% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 50.9% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 50.5% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 50.5% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 50.5% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 50.5% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 50.4% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 50.3% identity Open · Scan
ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q9H116_GZF1_HUMAN:409:514_5ei9_E_1 ModCRE Homology model CCCCCCAGGGGGGGCCC Region 409-514 · 1 3D model Open · Scan
TFS_sp_Q9H116_GZF1_HUMAN:433:541_2jpa_A_1 ModCRE Homology model ACCCGGCGTGGCCC Region 433-541 · 1 3D model Open · Scan
TFS_sp_Q9H116_GZF1_HUMAN:434:544_6e93_A_1 ModCRE Homology model TTGCGGCTCGCGAGGTTG Region 434-544 · 1 3D model Open · Scan
TFS_sp_Q9H116_GZF1_HUMAN:434:544_6e94_A_1 ModCRE Homology model TTGCGACTCGCGGGGTTG Region 434-544 · 1 3D model Open · Scan
TFS_sp_Q9H116_GZF1_HUMAN:488:573_1g2d_C_1 ModCRE Homology model CCGCCAGAAGACGTG Region 488-573 · 1 3D model Open · Scan
TFS_sp_Q9H116_GZF1_HUMAN:488:573_1g2f_C_1 ModCRE Homology model CCGACAAAAAAAACC Region 488-573 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 711 aa
318-604

Region 318-604 6 PWM

Residues
287 aa
Domains
PF00096 · Zinc finger, C2H2 type PF13894 · C2H2-type zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF13912 · C2H2-type zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
12 active PDBs · 6 summary rows
Templates
1G2D, 1G2F, 1LLM, 2I13, 2JPA, 5EI9, 5V3J, 5V3M, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 6 summary rows
Region 318-60412 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q9H116_GZF1_HUMAN:517:568_1llm_C_1 1llm 517-568 View model · PDB
Predicted = Low TFS_sp_Q9H116_GZF1_HUMAN:318:597_5v3j_E_1 5v3j 318-597 View model · PDB
Predicted = Low TFS_sp_Q9H116_GZF1_HUMAN:318:597_5v3m_C_1 5v3m 318-597 View model · PDB
Predicted = Low TFS_sp_Q9H116_GZF1_HUMAN:344:604_5wjq_D_1 5wjq 344-604 View model · PDB
Predicted = Low TFS_sp_Q9H116_GZF1_HUMAN:409:514_5ei9_E_1 5ei9 409-514 View model · PDB
Predicted = Low TFS_sp_Q9H116_GZF1_HUMAN:425:569_2i13_A_1 2i13 425-569 View model · PDB
Predicted = Low TFS_sp_Q9H116_GZF1_HUMAN:431:573_6ml7_A_1 6ml7 431-573 View model · PDB
Predicted = Low TFS_sp_Q9H116_GZF1_HUMAN:433:541_2jpa_A_1 2jpa 433-541 View model · PDB
Predicted = Low TFS_sp_Q9H116_GZF1_HUMAN:434:544_6e93_A_1 6e93 434-544 View model · PDB
Predicted = Low TFS_sp_Q9H116_GZF1_HUMAN:434:544_6e94_A_1 6e94 434-544 View model · PDB
Predicted = Low TFS_sp_Q9H116_GZF1_HUMAN:488:573_1g2d_C_1 1g2d 488-573 View model · PDB
Predicted = Low TFS_sp_Q9H116_GZF1_HUMAN:488:573_1g2f_C_1 1g2f 488-573 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 317:627 425 569 P:A · DNA:C,D 49.0% / 66.2% 94 View · PDB TFS_sp_Q9H116_GZF1_HUMAN:425:569_2i13_A_1
1 1llm 317:627 517,517 568,568 P:C,D · DNA:A,B 46.2% / 71.2% 59,61 View · PDB DIMER_sp_Q9H116_GZF1_HUMAN:517:568_1llm_C_1
5 6ml7 317:627 431 573 P:A · DNA:E,F 42.7% / 61.5% 100 View · PDB TFS_sp_Q9H116_GZF1_HUMAN:431:573_6ml7_A_1
1 5v3m 317:627 318 597 P:C · DNA:A,B 42.1% / 55.7% 98 View · PDB TFS_sp_Q9H116_GZF1_HUMAN:318:597_5v3m_C_1
2 5v3j 317:627 318 597 P:E · DNA:A,B 42.1% / 55.7% 98 View · PDB TFS_sp_Q9H116_GZF1_HUMAN:318:597_5v3j_E_1
3 5wjq 317:627 344 604 P:D · DNA:A,B 41.8% / 56.3% 91 View · PDB TFS_sp_Q9H116_GZF1_HUMAN:344:604_5wjq_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
22-130PF00651BTB/POZ domainNo overlap with loaded model regions
348-371PF00096Zinc finger, C2H2 typeoverlaps 318-604
377-400PF13894C2H2-type zinc fingeroverlaps 318-604
407-429PF00096Zinc finger, C2H2 typeoverlaps 318-604
437-457PF00096Zinc finger, C2H2 typeoverlaps 318-604
463-485PF13912C2H2-type zinc fingeroverlaps 318-604
491-513PF00096Zinc finger, C2H2 typeoverlaps 318-604
519-541PF00096Zinc finger, C2H2 typeoverlaps 318-604
549-569PF00096Zinc finger, C2H2 typeoverlaps 318-604
575-597PF00096Zinc finger, C2H2 typeoverlaps 318-604