ModCRE DB

Transcription factor

Q9H2S9 - IKZF4

Zinc finger protein Eos (Ikaros family zinc finger protein 4)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 585 aa

9 Generated PWM 13 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)1
MotifPredictionSourceDNA bindingSupportLogoActions
MA1508.1 NN 70-40% JASPAR GAAACAGGAAGT 52.6% identity Open · Scan
ModCRE8
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q9H2S9_IKZF4_HUMAN:185:233_1llm_C_1 ModCRE Homology model CCGGCGCGCATG Region 185-233 · 1 3D model Open · Scan
DIMER_sp_Q9H2S9_IKZF4_HUMAN:216:268_1hwt_C_1 ModCRE Homology model CGCCGGGCCGGCCTTTTCC Region 216-268 · 1 3D model Open · Scan
DIMER_sp_Q9H2S9_IKZF4_HUMAN:224:268_2hap_D_1 ModCRE Homology model GAAATAAACCCAATGGG Region 224-268 · 1 3D model Open · Scan
TFS_sp_Q9H2S9_IKZF4_HUMAN:160:271_5k5h_A_1 ModCRE Homology model CGGTCCCTCCTT Region 160-271 · 1 3D model Open · Scan
TFS_sp_Q9H2S9_IKZF4_HUMAN:164:237_5keb_A_1 ModCRE Homology model CCGGCGCATT Region 164-237 · 1 3D model Open · Scan
TFS_sp_Q9H2S9_IKZF4_HUMAN:185:238_1f2i_G_1 ModCRE Homology model GGGGGCCCGCT Region 185-238 · 1 3D model Open · Scan
TFS_sp_Q9H2S9_IKZF4_HUMAN:185:238_1f2i_H_1 ModCRE Homology model CGGCCACCCA Region 185-238 · 1 3D model Open · Scan
TFS_sp_Q9H2S9_IKZF4_HUMAN:189:237_4is1_C_1 ModCRE Homology model TACGATTTTT Region 189-237 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 585 aa
160-271

Region 160-271 8 PWM

Residues
112 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
13 active PDBs · 8 summary rows
Templates
1F2I, 1HWT, 1LLM, 2HAP, 2I13, 4IS1, 5EGB, 5EH2, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
13 active PDB models 8 summary rows
Region 160-27113 models · 8 summary rows
Actions
Predicted = Low DIMER_sp_Q9H2S9_IKZF4_HUMAN:185:233_1llm_C_1 1llm 185-233 View model · PDB
Predicted = Low DIMER_sp_Q9H2S9_IKZF4_HUMAN:216:268_1hwt_C_1 1hwt 216-268 View model · PDB
Predicted = Low DIMER_sp_Q9H2S9_IKZF4_HUMAN:224:268_2hap_D_1 2hap 224-268 View model · PDB
Predicted = Low TFS_sp_Q9H2S9_IKZF4_HUMAN:160:267_2i13_A_1 2i13 160-267 View model · PDB
Predicted = Low TFS_sp_Q9H2S9_IKZF4_HUMAN:160:268_5wjq_D_1 5wjq 160-268 View model · PDB
Predicted = Low TFS_sp_Q9H2S9_IKZF4_HUMAN:160:271_5k5h_A_1 5k5h 160-271 View model · PDB
Predicted = Low TFS_sp_Q9H2S9_IKZF4_HUMAN:161:267_5egb_A_1 5egb 161-267 View model · PDB
Predicted = Low TFS_sp_Q9H2S9_IKZF4_HUMAN:161:267_5eh2_F_1 5eh2 161-267 View model · PDB
Predicted = Low TFS_sp_Q9H2S9_IKZF4_HUMAN:161:267_5ei9_E_1 5ei9 161-267 View model · PDB
Predicted = Low TFS_sp_Q9H2S9_IKZF4_HUMAN:164:237_5keb_A_1 5keb 164-237 View model · PDB
Predicted = Low TFS_sp_Q9H2S9_IKZF4_HUMAN:185:238_1f2i_G_1 1f2i 185-238 View model · PDB
Predicted = Low TFS_sp_Q9H2S9_IKZF4_HUMAN:185:238_1f2i_H_1 1f2i 185-238 View model · PDB
Predicted = Low TFS_sp_Q9H2S9_IKZF4_HUMAN:189:237_4is1_C_1 4is1 189-237 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 2i13 158:275 160 267 P:A · DNA:C,D 43.5% / 58.3% 68 View · PDB TFS_sp_Q9H2S9_IKZF4_HUMAN:160:267_2i13_A_1
2 5ei9 158:275 161 267 P:E · DNA:A,B 41.1% / 55.1% 91 View · PDB TFS_sp_Q9H2S9_IKZF4_HUMAN:161:267_5ei9_E_1
3 5egb 158:275 161 267 P:A · DNA:C,D 41.1% / 55.1% 91 View · PDB TFS_sp_Q9H2S9_IKZF4_HUMAN:161:267_5egb_A_1
4 5eh2 158:275 161 267 P:F · DNA:C,D 41.1% / 55.1% 93 View · PDB TFS_sp_Q9H2S9_IKZF4_HUMAN:161:267_5eh2_F_1
5 5wjq 158:275 160 268 P:D · DNA:A,B 40.4% / 58.7% 36 View · PDB TFS_sp_Q9H2S9_IKZF4_HUMAN:160:268_5wjq_D_1
1 1llm 158:275 185,185 233,233 P:C,D · DNA:A,B 38.8% / 53.1% 56,57 View · PDB DIMER_sp_Q9H2S9_IKZF4_HUMAN:185:233_1llm_C_1
2 2hap 158:275 224,224 268,268 P:C,D · DNA:A,B 24.4% / 46.7% 59,60 View · PDB DIMER_sp_Q9H2S9_IKZF4_HUMAN:224:268_2hap_D_1
3 1hwt 158:275 216,216 268,268 P:C,D · DNA:A,B 22.6% / 43.4% 75,71 View · PDB DIMER_sp_Q9H2S9_IKZF4_HUMAN:216:268_1hwt_C_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
187-209PF00096Zinc finger, C2H2 typeoverlaps 160-271
215-237PF00096Zinc finger, C2H2 typeoverlaps 160-271
248-271PF00096Zinc finger, C2H2 typeoverlaps 160-271