ModCRE DB

Transcription factor

Q9H2Z4 - NKX2-4

Homeobox protein Nkx-2.4 (Homeobox protein NK-2 homolog D)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 354 aa

73 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known2
MotifPredictionSourceDNA bindingSupportLogoActions
MA2003.1 Known JASPAR CCACTTGAAC Direct PWM Open · Scan
MA2003.2 Known JASPAR CCACTTGA Direct PWM Open · Scan
Nearest Neighbor (>70%)8
MotifPredictionSourceDNA bindingSupportLogoActions
M00438_2.00 NN 70+% CisBP TTTAAGTGC 79.7% identity Open · Scan
M02181_2.00 NN 70+% CisBP TTAAGTGGT 77.2% identity Open · Scan
M00376_2.00 NN 70+% CisBP TCAAGTGCTT 76.1% identity Open · Scan
M00497_2.00 NN 70+% CisBP TTAAGTGGT 73.7% identity Open · Scan
M05042_2.00 NN 70+% CisBP GTCAAGTGGT 72.7% identity Open · Scan
MA0672.1 NN 70+% JASPAR ACCACTTGAA 72.7% identity Open · Scan
MA0063.1 NN 70+% JASPAR TTAATTG 70.7% identity Open · Scan
MA0063.2 NN 70+% JASPAR ACCACTCAAAA 70.7% identity Open · Scan
Nearest Neighbor (70% - 40%)63
MotifPredictionSourceDNA bindingSupportLogoActions
MA1645.1 NN 70-40% JASPAR TAACCACTCAAGAA 69.6% identity Open · Scan
M00496_2.00 NN 70-40% CisBP TTAAGTGGTT 67.0% identity Open · Scan
MA0124.1 NN 70-40% JASPAR ATACTTA 66.1% identity Open · Scan
MA0124.2 NN 70-40% JASPAR ACCACTTAA 66.1% identity Open · Scan
M06378_2.00 NN 70-40% CisBP GCTCAAGTGC 66.0% identity Open · Scan
M06286_2.00 NN 70-40% CisBP CTTAAGTG 65.5% identity Open · Scan
M00385_2.00 NN 70-40% CisBP TTAAGTGG 62.9% identity Open · Scan
M09146_2.00 NN 70-40% CisBP CTTGAGTGGC 62.8% identity Open · Scan
MA0673.1 NN 70-40% JASPAR CCACTTGAA 60.0% identity Open · Scan
M00520_2.00 NN 70-40% CisBP CTTAAGTGCT 59.0% identity Open · Scan
MA0666.1 NN 70-40% JASPAR CCAATTAG 56.1% identity Open · Scan
MA0709.1 NN 70-40% JASPAR CCAATTAA 56.1% identity Open · Scan
M00526_2.00 NN 70-40% CisBP ATTAATTA 55.9% identity Open · Scan
M02106_2.00 NN 70-40% CisBP ATATTAATTGGTT 55.9% identity Open · Scan
M06232_2.00 NN 70-40% CisBP TTAATGA 55.9% identity Open · Scan
M10754_2.00 NN 70-40% CisBP CAAGTGCGTG 55.9% identity Open · Scan
MA0876.1 NN 70-40% JASPAR CCAATTAA 55.9% identity Open · Scan
MA0898.1 NN 70-40% JASPAR ACAAGCAATTAAAGAAT 55.9% identity Open · Scan
MA1577.1 NN 70-40% JASPAR CTAATTAG 55.9% identity Open · Scan
M02128_2.00 NN 70-40% CisBP ATTAATTA 55.7% identity Open · Scan
MA0897.1 NN 70-40% JASPAR ACAAGCAATTAAAGAAT 55.7% identity Open · Scan
M03234_2.00 NN 70-40% CisBP TTTTAATTGGT 55.5% identity Open · Scan
M00465_2.00 NN 70-40% CisBP TTAATTAG 55.1% identity Open · Scan
MA0635.1 NN 70-40% JASPAR GCTAAACGGT 55.1% identity Open · Scan
MA0699.1 NN 70-40% JASPAR GCCAATTAGC 55.1% identity Open · Scan
M05179_2.00 NN 70-40% CisBP ATAATTGC 54.3% identity Open · Scan
MA0708.1 NN 70-40% JASPAR CCAATTAA 54.3% identity Open · Scan
MA0879.1 NN 70-40% JASPAR CCTAATTATC 54.3% identity Open · Scan
M05392_2.00 NN 70-40% CisBP GTTAAGTGC 54.2% identity Open · Scan
M00451_2.00 NN 70-40% CisBP ATTAATTA 53.8% identity Open · Scan
MA0122.1 NN 70-40% JASPAR TTAAGTGGA 53.4% identity Open · Scan
MA0122.2 NN 70-40% JASPAR ACCACTTAA 53.4% identity Open · Scan
MA0618.1 NN 70-40% JASPAR TTAATTAG 53.4% identity Open · Scan
MA0877.1 NN 70-40% JASPAR GCTAATTGCT 53.4% identity Open · Scan
MA0877.2 NN 70-40% JASPAR CTAAACGG 53.4% identity Open · Scan
M06359_2.00 NN 70-40% CisBP TTTAATTA 52.9% identity Open · Scan
M01503_2.00 NN 70-40% CisBP TTAATTAC 52.6% identity Open · Scan
M03777_2.00 NN 70-40% CisBP GTAATTGC 52.6% identity Open · Scan
M04906_2.00 NN 70-40% CisBP ATAACGAC 52.6% identity Open · Scan
M06312_2.00 NN 70-40% CisBP TTAATTA 52.6% identity Open · Scan
M09195_2.00 NN 70-40% CisBP TAATTATAGGT 52.6% identity Open · Scan
MA0880.1 NN 70-40% JASPAR CCAATTAC 52.6% identity Open · Scan
MA0882.1 NN 70-40% JASPAR CCAATTAC 52.6% identity Open · Scan
MA0885.1 NN 70-40% JASPAR GCAATTAA 52.6% identity Open · Scan
MA1476.1 NN 70-40% JASPAR GCAATTAC 52.6% identity Open · Scan
M06290_2.00 NN 70-40% CisBP TTTAATTA 52.5% identity Open · Scan
MA0675.1 NN 70-40% JASPAR CTAATTAA 52.0% identity Open · Scan
M03798_2.00 NN 70-40% CisBP GGTAATTAGC 51.7% identity Open · Scan
M06339_2.00 NN 70-40% CisBP TTTAATTGG 51.7% identity Open · Scan
M02164_2.00 NN 70-40% CisBP GTAATGGGCT 50.9% identity Open · Scan
M06489_2.00 NN 70-40% CisBP TTAATTA 50.9% identity Open · Scan
M00462_2.00 NN 70-40% CisBP CTAATTG 50.8% identity Open · Scan
M05003_2.00 NN 70-40% CisBP ATAACGAC 50.8% identity Open · Scan
M06323_2.00 NN 70-40% CisBP ATTAATTG 50.8% identity Open · Scan
MA0889.1 NN 70-40% JASPAR ACTAATTAGC 50.8% identity Open · Scan
MA0890.1 NN 70-40% JASPAR ACCAATTAGC 50.8% identity Open · Scan
M00388_2.00 NN 70-40% CisBP CTAATTGCTT 50.0% identity Open · Scan
M02148_2.00 NN 70-40% CisBP CTAATTAG 50.0% identity Open · Scan
M02149_2.00 NN 70-40% CisBP TCAAGTGCTT 50.0% identity Open · Scan
M06361_2.00 NN 70-40% CisBP TTTAATTA 50.0% identity Open · Scan
M09565_2.00 NN 70-40% CisBP GTTAATGGCC 50.0% identity Open · Scan
M10805_2.00 NN 70-40% CisBP GGACAAATAGCCC 50.0% identity Open · Scan
MA0707.1 NN 70-40% JASPAR GGTAATTAAA 50.0% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 354 aa
189-245

Region 189-245 0 PWM

Residues
57 aa
Domains
PF00046 · Homeodomain
3D models
1 active PDB
Templates
3RKQ
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 189-2451 model
Actions
Predicted = Low DIMER_Q9H2Z4:189:245_3rkq_A_1 3rkq 189-245 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
190-246PF00046Homeodomainoverlaps 189-245