ModCRE DB

Transcription factor

Q9HD90 - NEUROD4

Neurogenic differentiation factor 4 (NeuroD4) (Class A basic helix-loop-helix protein 4) (bHLHa4) (Protein atonal homolog 3) (ATH-3) (Atoh3)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 331 aa

39 Generated PWM 13 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)26
MotifPredictionSourceDNA bindingSupportLogoActions
MA0623.1 NN 70-40% JASPAR ACCATATGGT 67.2% identity Open · Scan
MA0623.2 NN 70-40% JASPAR GACATATGTC 67.2% identity Open · Scan
MA0669.1 NN 70-40% JASPAR AACATATGTC 66.0% identity Open · Scan
MA1467.1 NN 70-40% JASPAR AACAGCTGTC 60.9% identity Open · Scan
M05967_2.00 NN 70-40% CisBP TGACATATGG 60.6% identity Open · Scan
MA0827.1 NN 70-40% JASPAR ACCATATGTT 59.3% identity Open · Scan
MA0461.1 NN 70-40% JASPAR CAGATGGC 58.7% identity Open · Scan
M01729_2.00 NN 70-40% CisBP AACATATGGT 57.6% identity Open · Scan
M05980_2.00 NN 70-40% CisBP CACAGCTGAC 57.6% identity Open · Scan
M05986_2.00 NN 70-40% CisBP ACCGCACCATCTGTC 57.6% identity Open · Scan
MA0818.1 NN 70-40% JASPAR ACCATATGTT 57.6% identity Open · Scan
MA1468.1 NN 70-40% JASPAR AACATATGTC 57.1% identity Open · Scan
M02784_2.00 NN 70-40% CisBP ACCATATGTT 55.9% identity Open · Scan
MA0817.1 NN 70-40% JASPAR AAACATATGTTT 55.9% identity Open · Scan
M05951_2.00 NN 70-40% CisBP ACCACCTGT 54.5% identity Open · Scan
MA0678.1 NN 70-40% JASPAR ACCATATGGT 54.0% identity Open · Scan
M05952_2.00 NN 70-40% CisBP ACCATCTGCCG 53.5% identity Open · Scan
M05962_2.00 NN 70-40% CisBP CCACCTGCC 53.4% identity Open · Scan
MA0607.1 NN 70-40% JASPAR CCATATGT 53.4% identity Open · Scan
MA1472.1 NN 70-40% JASPAR AACAGCTGTT 53.4% identity Open · Scan
MA1109.1 NN 70-40% JASPAR GGACAGATGGCAG 52.6% identity Open · Scan
M06000_2.00 NN 70-40% CisBP CCAGATGGCACGGACACAACA 51.7% identity Open · Scan
M02794_2.00 NN 70-40% CisBP AACACCTGTG 50.8% identity Open · Scan
M04213_2.00 NN 70-40% CisBP CAACATATGTCG 50.8% identity Open · Scan
M03621_2.00 NN 70-40% CisBP AAAACAGCTGTTTT 50.0% identity Open · Scan
MA1485.1 NN 70-40% JASPAR GCAACAGCTGTTAC 50.0% identity Open · Scan
ModCRE13
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q9HD90_NDF4_HUMAN:87:145_2ql2_B_1 ModCRE Homology model GTAAGCATATGCCCCC Region 87-145 · 1 3D model Open · Scan
DIMER_sp_Q9HD90_NDF4_HUMAN:88:141_7z5i_B_1 ModCRE Homology model GGTGCCCATATGTGTACC Region 88-141 · 1 3D model Open · Scan
DIMER_sp_Q9HD90_NDF4_HUMAN:88:142_7z5k_B_1 ModCRE Homology model AGTAGCCAGCTGGGGAGG Region 88-142 · 1 3D model Open · Scan
DIMER_sp_Q9HD90_NDF4_HUMAN:88:143_1mdy_B_1 ModCRE Homology model TGCCCATATGGGCC Region 88-143 · 1 3D model Open · Scan
DIMER_sp_Q9HD90_NDF4_HUMAN:88:143_2ypa_A_1 ModCRE Homology model AACCATATGGG Region 88-143 · 1 3D model Open · Scan
DIMER_sp_Q9HD90_NDF4_HUMAN:88:143_2ypb_A_1 ModCRE Homology model CACCATATGGG Region 88-143 · 1 3D model Open · Scan
TFS_sp_Q9HD90_NDF4_HUMAN:87:145_2ql2_B_1 ModCRE Homology model TCAAAAATATGCTTCC Region 87-145 · 1 3D model Open · Scan
TFS_sp_Q9HD90_NDF4_HUMAN:88:141_7z5i_B_1 ModCRE Homology model GGTACACATATGGGCACC Region 88-141 · 1 3D model Open · Scan
TFS_sp_Q9HD90_NDF4_HUMAN:88:142_7z5k_B_1 ModCRE Homology model CCTCCCCAGCTGGCTACT Region 88-142 · 1 3D model Open · Scan
TFS_sp_Q9HD90_NDF4_HUMAN:88:143_1mdy_A_1 ModCRE Homology model GCCCCATATGTGCA Region 88-143 · 1 3D model Open · Scan
TFS_sp_Q9HD90_NDF4_HUMAN:88:143_1mdy_B_1 ModCRE Homology model TGCCCATATGTGCA Region 88-143 · 1 3D model Open · Scan
TFS_sp_Q9HD90_NDF4_HUMAN:88:143_2ypa_A_1 ModCRE Homology model CCCATATGGGT Region 88-143 · 1 3D model Open · Scan
TFS_sp_Q9HD90_NDF4_HUMAN:88:143_2ypb_A_1 ModCRE Homology model CCCATATGGTG Region 88-143 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 331 aa
84-145

Region 84-145 13 PWM

Residues
62 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
13 active PDBs · 10 summary rows
Templates
1MDY, 2QL2, 2YPA, 2YPB, 7Z5I, 7Z5K
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
13 active PDB models 10 summary rows
Region 84-14513 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q9HD90_NDF4_HUMAN:87:145_2ql2_B_1 2ql2 87-145 View model · PDB
Predicted = Low DIMER_sp_Q9HD90_NDF4_HUMAN:88:141_7z5i_B_1 7z5i 88-141 View model · PDB
Predicted = Low DIMER_sp_Q9HD90_NDF4_HUMAN:88:142_7z5k_B_1 7z5k 88-142 View model · PDB
Predicted = Low DIMER_sp_Q9HD90_NDF4_HUMAN:88:143_1mdy_B_1 1mdy 88-143 View model · PDB
Predicted = Low DIMER_sp_Q9HD90_NDF4_HUMAN:88:143_2ypa_A_1 2ypa 88-143 View model · PDB
Predicted = Low DIMER_sp_Q9HD90_NDF4_HUMAN:88:143_2ypb_A_1 2ypb 88-143 View model · PDB
Predicted = Low TFS_sp_Q9HD90_NDF4_HUMAN:87:145_2ql2_B_1 2ql2 87-145 View model · PDB
Predicted = Low TFS_sp_Q9HD90_NDF4_HUMAN:88:141_7z5i_B_1 7z5i 88-141 View model · PDB
Predicted = Low TFS_sp_Q9HD90_NDF4_HUMAN:88:142_7z5k_B_1 7z5k 88-142 View model · PDB
Predicted = Low TFS_sp_Q9HD90_NDF4_HUMAN:88:143_1mdy_A_1 1mdy 88-143 View model · PDB
Predicted = Low TFS_sp_Q9HD90_NDF4_HUMAN:88:143_1mdy_B_1 1mdy 88-143 View model · PDB
Predicted = Low TFS_sp_Q9HD90_NDF4_HUMAN:88:143_2ypa_A_1 2ypa 88-143 View model · PDB
Predicted = Low TFS_sp_Q9HD90_NDF4_HUMAN:88:143_2ypb_A_1 2ypb 88-143 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 2ql2 87:145 87 145 P:B · DNA:E,F 83.1% / 94.9% 100 View · PDB TFS_sp_Q9HD90_NDF4_HUMAN:87:145_2ql2_B_1
1 2ypb 87:145 88,84 143,122 P:A,B · DNA:E,F 44.6% / 64.3% 83,52 View · PDB DIMER_sp_Q9HD90_NDF4_HUMAN:88:143_2ypb_A_1
2 2ypb 87:145 88,84 143,122 P:A,B · DNA:E,F 44.6% / 64.3% 83,52 View · PDB TFS_sp_Q9HD90_NDF4_HUMAN:88:143_2ypb_A_1
2 2ypa 87:145 88,84 143,122 P:A,B · DNA:E,F 44.6% / 64.3% 83,53 View · PDB DIMER_sp_Q9HD90_NDF4_HUMAN:88:143_2ypa_A_1
3 2ypa 87:145 88,84 143,122 P:A,B · DNA:E,F 44.6% / 64.3% 83,53 View · PDB TFS_sp_Q9HD90_NDF4_HUMAN:88:143_2ypa_A_1
4 7z5i 87:145 88,88 141,141 P:A,B · DNA:E,F 40.7% / 55.6% 94,94 View · PDB DIMER_sp_Q9HD90_NDF4_HUMAN:88:141_7z5i_B_1
5 7z5i 87:145 88,88 141,141 P:A,B · DNA:E,F 40.7% / 55.6% 94,94 View · PDB TFS_sp_Q9HD90_NDF4_HUMAN:88:141_7z5i_B_1
3 7z5k 87:145 88,88 141,142 P:A,B · DNA:E,F 40.0% / 56.4% 94,96 View · PDB DIMER_sp_Q9HD90_NDF4_HUMAN:88:142_7z5k_B_1
4 7z5k 87:145 88,88 141,142 P:A,B · DNA:E,F 40.0% / 56.4% 94,96 View · PDB TFS_sp_Q9HD90_NDF4_HUMAN:88:142_7z5k_B_1
5 1mdy 87:145 88,88 143,143 P:A,B · DNA:E,F 39.3% / 55.4% 80,88 View · PDB DIMER_sp_Q9HD90_NDF4_HUMAN:88:143_1mdy_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
88-138PF00010Helix-loop-helix DNA-binding domainoverlaps 84-145
146-264PF12533Neuronal helix-loop-helix transcription factorNo overlap with loaded model regions