Transcription factor

Q9NQB0 - TCF7L2

Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 619 aa

7 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known7

Motif	Prediction	Source	DNA binding	Support	Actions
MA0523.1	Known	JASPAR	AAAGATCAAAGGAA	Direct PWM	Open · Scan
MA0523.2	Known	JASPAR	AGATCAAAG	Direct PWM	Open · Scan
M08167_2.00	Known	CisBP	AAAGATCAAAGGAA	Direct PWM	Open · Scan
M09393_2.00	Known	CisBP	GGCAGCTGGG	Direct PWM	Open · Scan
M09394_2.00	Known	CisBP	CCACATCAAAGGG	Direct PWM	Open · Scan
M09638_2.00	Known	CisBP	CCTTTGAAGT	Direct PWM	Open · Scan
TF7L2_HUMAN.H11MO.0.A	Known	HOCOMOCO	CCCTTTGATGTGG	Direct PWM	Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 619 aa

349-420

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 349-4201 model

				Actions
Predicted = Low	TFS_Q9NQB0:349:420_3u2b_C_1	3u2b	349-420	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
5-259	PF08347	N-terminal CTNNB1 binding	No overlap with loaded model regions
350-418	PF00505	HMG (high mobility group) box	overlaps 349-420
462-489	PF27556	Zinc finger protein 704 C-terminal domain	No overlap with loaded model regions