Transcription factor

Q9NYT6 - ZNF226

Zinc finger protein 226

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 803 aa

112 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)105

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	68.2% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	68.2% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	68.2% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	67.8% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	67.0% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	65.4% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	64.7% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	64.7% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	64.7% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	64.7% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	62.3% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	60.0% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	59.6% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	59.2% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	58.6% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	58.6% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	58.5% identity		Open · Scan
M08887_2.00	NN 70-40%	CisBP	CCTCCTCCAGGAAGCCTTCCCTGA	57.6% identity		Open · Scan
M08314_2.00	NN 70-40%	CisBP	ATTCATCAAGGTCCTCAACAATGG	57.4% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	57.4% identity		Open · Scan
M07613_2.00	NN 70-40%	CisBP	TCACTCAGTCATTCA	57.0% identity		Open · Scan
M07761_2.00	NN 70-40%	CisBP	CTGATTATTCACCCA	56.8% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	56.7% identity		Open · Scan
M07764_2.00	NN 70-40%	CisBP	CTGCACTCTCCCCTTCCCCCCCTCCCC	56.6% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	56.6% identity		Open · Scan
M07715_2.00	NN 70-40%	CisBP	CCGCCGCCGCCGTGG	56.2% identity		Open · Scan
M07590_2.00	NN 70-40%	CisBP	TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT	56.1% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	55.6% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	55.4% identity		Open · Scan
M07565_2.00	NN 70-40%	CisBP	CCTCTGGGGGCTCGTCCA	55.4% identity		Open · Scan
M08311_2.00	NN 70-40%	CisBP	CTGGAACAGAAGGGGCGA	55.4% identity		Open · Scan
M07667_2.00	NN 70-40%	CisBP	CCGCACAGGCCCCCGGGCCCC	55.3% identity		Open · Scan
M07687_2.00	NN 70-40%	CisBP	ACAAATAAGGTTCTTGTGCCCCCTGCT	55.3% identity		Open · Scan
M07714_2.00	NN 70-40%	CisBP	AGCCCATTGGGGCCTATGCCC	55.3% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	55.2% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	55.2% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	55.1% identity		Open · Scan
M08347_2.00	NN 70-40%	CisBP	GCCCTGGGCAGC	55.0% identity		Open · Scan
MA1599.1	NN 70-40%	JASPAR	CGGGCCAAGCCCCTAT	54.9% identity		Open · Scan
M08381_2.00	NN 70-40%	CisBP	ACATTTTGTCCTCCTAGTCCT	54.6% identity		Open · Scan
M07586_2.00	NN 70-40%	CisBP	GGGACCCGGGTGGGGGCGTCCCCC	54.5% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	54.5% identity		Open · Scan
M07635_2.00	NN 70-40%	CisBP	AAGTTTTCTTGTATTATATCT	54.2% identity		Open · Scan
M07657_2.00	NN 70-40%	CisBP	CCCCTGCATGTCCCCATTTTT	54.2% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	54.2% identity		Open · Scan
M08252_2.00	NN 70-40%	CisBP	CCGGCTCCAGCACCC	54.1% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	54.0% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	53.9% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	53.9% identity		Open · Scan
M08944_2.00	NN 70-40%	CisBP	TACCATGCTGTTTTGATTAC	53.9% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	53.7% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	53.7% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	53.7% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	53.6% identity		Open · Scan
M08921_2.00	NN 70-40%	CisBP	CCTCATTCTTCTTGGACATG	53.5% identity		Open · Scan
M04505_2.00	NN 70-40%	CisBP	AGCTTTTCCCACAC	53.4% identity		Open · Scan
M07566_2.00	NN 70-40%	CisBP	TCAAACCATCCTTGC	53.4% identity		Open · Scan
M08860_2.00	NN 70-40%	CisBP	TCTTATAAGGGCACTAATCCCATT	53.4% identity		Open · Scan
M08908_2.00	NN 70-40%	CisBP	GCTGCTGCTTCTGCTG	53.4% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	53.3% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	53.1% identity		Open · Scan
M01538_2.00	NN 70-40%	CisBP	GCCCCTGA	53.1% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	53.1% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	52.8% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	52.8% identity		Open · Scan
M08371_2.00	NN 70-40%	CisBP	CCAGACTTGTCCTCT	52.8% identity		Open · Scan
M07685_2.00	NN 70-40%	CisBP	CTTTCCAGCCAC	52.6% identity		Open · Scan
M07723_2.00	NN 70-40%	CisBP	CCGCTGCTCCCTGCT	52.6% identity		Open · Scan
M08255_2.00	NN 70-40%	CisBP	CTCTTCCGGT	52.6% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	52.6% identity		Open · Scan
MA1597.1	NN 70-40%	JASPAR	CCCAGGGAAGCCATTTC	52.6% identity		Open · Scan
M07620_2.00	NN 70-40%	CisBP	TTGGATCTGTGGATTCATGTCTTTCAT	52.5% identity		Open · Scan
M08330_2.00	NN 70-40%	CisBP	TGGGTGCCGGACTGCTGTTCC	52.5% identity		Open · Scan
M00134_2.00	NN 70-40%	CisBP	GCCACGCCCA	52.4% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	52.4% identity		Open · Scan
M07754_2.00	NN 70-40%	CisBP	CGCCCCCTCCCT	52.3% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	52.2% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	52.1% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	52.0% identity		Open · Scan
M08309_2.00	NN 70-40%	CisBP	AAAAACCCCCCTGCAGAGCCCAGCCCT	51.8% identity		Open · Scan
M07767_2.00	NN 70-40%	CisBP	AAAAACCCCAGA	51.7% identity		Open · Scan
M08399_2.00	NN 70-40%	CisBP	TACTCTGGGGCCACATGACTC	51.7% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	51.6% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	51.3% identity		Open · Scan
M07662_2.00	NN 70-40%	CisBP	CCTGTGTCCTCCCTGGTCCCC	51.3% identity		Open · Scan
M08949_2.00	NN 70-40%	CisBP	TTCTATTTCTTCTTGTGTCA	51.3% identity		Open · Scan
M07646_2.00	NN 70-40%	CisBP	CTTTTTTTT	51.2% identity		Open · Scan
M05853_2.00	NN 70-40%	CisBP	CCACCTTTAGCCATATCT	51.1% identity		Open · Scan
M00764_2.00	NN 70-40%	CisBP	GTCTACAC	51.0% identity		Open · Scan
M08274_2.00	NN 70-40%	CisBP	TTACTTGCAGCCCAACGCATTCCTAAC	51.0% identity		Open · Scan
MA1646.1	NN 70-40%	JASPAR	AAACAGAAGCAG	51.0% identity		Open · Scan
MA0130.1	NN 70-40%	JASPAR	ATCCAC	50.6% identity		Open · Scan
M07747_2.00	NN 70-40%	CisBP	TGGTCTATAAAGGGCCTGGTT	50.5% identity		Open · Scan
M08917_2.00	NN 70-40%	CisBP	GCTGAGCCATGTGGGGTGCT	50.5% identity		Open · Scan
M00609_2.00	NN 70-40%	CisBP	GGAAGCCCTA	50.4% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	50.4% identity		Open · Scan
MA1589.1	NN 70-40%	JASPAR	TAGGAGTGGAATTGCTGGGTC	50.4% identity		Open · Scan
M07701_2.00	NN 70-40%	CisBP	CCTGGGCTAGGCCCTGGC	50.2% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	50.2% identity		Open · Scan
M07775_2.00	NN 70-40%	CisBP	GCCGAAACCCGGG	50.1% identity		Open · Scan
M00618_2.00	NN 70-40%	CisBP	TGCTACCGT	50.0% identity		Open · Scan
M01540_2.00	NN 70-40%	CisBP	CTCCCCC	50.0% identity		Open · Scan
M06179_2.00	NN 70-40%	CisBP	TAAGCCTATAGA	50.0% identity		Open · Scan
M08859_2.00	NN 70-40%	CisBP	CATTTTTTCCTCCTAGGCCT	50.0% identity		Open · Scan
M10303_2.00	NN 70-40%	CisBP	TACTGGGAATACC	50.0% identity		Open · Scan

ModCRE7

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_sp_Q9NYT6_ZN226_HUMAN:361:412_1llm_D_1	ModCRE	Homology model	GCCGCGCGCGGA	Region 361-412 · 1 3D model		Open · Scan
TFS_sp_Q9NYT6_ZN226_HUMAN:360:470_5ei9_E_1	ModCRE	Homology model	AGAACAAGCCGGGGGCC	Region 360-470 · 1 3D model		Open · Scan
TFS_sp_Q9NYT6_ZN226_HUMAN:668:777_5egb_A_1	ModCRE	Homology model	TTTCCCCCGGGAGACCGT	Region 668-777 · 1 3D model		Open · Scan
TFS_sp_Q9NYT6_ZN226_HUMAN:668:777_5ei9_E_1	ModCRE	Homology model	GCCCCCGGGGGGGGGACA	Region 668-777 · 1 3D model		Open · Scan
TFS_sp_Q9NYT6_ZN226_HUMAN:670:777_5eh2_F_1	ModCRE	Homology model	CCCCCCGGGGGGGGGCCGG	Region 670-777 · 1 3D model		Open · Scan
TFS_sp_Q9NYT6_ZN226_HUMAN:676:777_2jp9_A_1	ModCRE	Homology model	CAAGGGGGGTGGTACCG	Region 676-777 · 1 3D model		Open · Scan
TFS_sp_Q9NYT6_ZN226_HUMAN:696:781_1g2f_C_1	ModCRE	Homology model	TGGGGGAGGGGCGGG	Region 696-781 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 803 aa

316-666

668-781

Region 316-666 2 PWM

Residues

351 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

7 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

Region 668-781 5 PWM

Residues

114 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

5 active PDBs

Templates

1G2F, 2JP9, 5EGB, 5EH2, 5EI9

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

12 active PDB models 6 summary rows

Region 316-6667 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_Q9NYT6_ZN226_HUMAN:361:412_1llm_D_1	1llm	361-412	View model · PDB
Predicted = Low	TFS_sp_Q9NYT6_ZN226_HUMAN:316:469_2i13_A_1	2i13	316-469	View model · PDB
Predicted = Low	TFS_sp_Q9NYT6_ZN226_HUMAN:360:470_5ei9_E_1	5ei9	360-470	View model · PDB
Predicted = Low	TFS_sp_Q9NYT6_ZN226_HUMAN:362:638_5v3j_E_1	5v3j	362-638	View model · PDB
Predicted = Low	TFS_sp_Q9NYT6_ZN226_HUMAN:362:638_5v3m_C_1	5v3m	362-638	View model · PDB
Predicted = Low	TFS_sp_Q9NYT6_ZN226_HUMAN:363:661_7w1m_H_1	7w1m	363-661	View model · PDB
Predicted = Low	TFS_sp_Q9NYT6_ZN226_HUMAN:388:666_5wjq_D_1	5wjq	388-666	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	316:779	316	469	P:A · DNA:C,D	60.4% / 71.4%	100	View · PDB TFS_sp_Q9NYT6_ZN226_HUMAN:316:469_2i13_A_1
1	5wjq	316:779	388	666	P:D · DNA:A,B	53.8% / 71.0%	99	View · PDB TFS_sp_Q9NYT6_ZN226_HUMAN:388:666_5wjq_D_1
2	5v3m	316:779	362	638	P:C · DNA:A,B	53.4% / 69.7%	100	View · PDB TFS_sp_Q9NYT6_ZN226_HUMAN:362:638_5v3m_C_1
3	5v3j	316:779	362	638	P:E · DNA:A,B	53.4% / 69.7%	100	View · PDB TFS_sp_Q9NYT6_ZN226_HUMAN:362:638_5v3j_E_1
1	1llm	316:779	361,361	412,412	P:C,D · DNA:A,B	48.1% / 65.4%	59,61	View · PDB DIMER_sp_Q9NYT6_ZN226_HUMAN:361:412_1llm_D_1
5	7w1m	316:779	363	661	P:H · DNA:F,G	36.0% / 51.6%	92	View · PDB TFS_sp_Q9NYT6_ZN226_HUMAN:363:661_7w1m_H_1

Region 668-7815 models

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	TFS_sp_Q9NYT6_ZN226_HUMAN:668:777_5egb_A_1	5egb	668-777	View model · PDB
Predicted = Low	TFS_sp_Q9NYT6_ZN226_HUMAN:668:777_5ei9_E_1	5ei9	668-777	View model · PDB
Predicted = Low	TFS_sp_Q9NYT6_ZN226_HUMAN:670:777_5eh2_F_1	5eh2	670-777	View model · PDB
Predicted = Low	TFS_sp_Q9NYT6_ZN226_HUMAN:676:777_2jp9_A_1	2jp9	676-777	View model · PDB
Predicted = Low	TFS_sp_Q9NYT6_ZN226_HUMAN:696:781_1g2f_C_1	1g2f	696-781	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
8-48	PF01352	KRAB box	No overlap with loaded model regions
252-272	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
308-329	PF00096	Zinc finger, C2H2 type	overlaps 316-666
335-357	PF00096	Zinc finger, C2H2 type	overlaps 316-666
363-385	PF00096	Zinc finger, C2H2 type	overlaps 316-666
391-413	PF00096	Zinc finger, C2H2 type	overlaps 316-666
419-441	PF00096	Zinc finger, C2H2 type	overlaps 316-666
447-469	PF00096	Zinc finger, C2H2 type	overlaps 316-666
475-497	PF00096	Zinc finger, C2H2 type	overlaps 316-666
503-525	PF00096	Zinc finger, C2H2 type	overlaps 316-666
531-553	PF00096	Zinc finger, C2H2 type	overlaps 316-666
559-581	PF00096	Zinc finger, C2H2 type	overlaps 316-666
587-609	PF00096	Zinc finger, C2H2 type	overlaps 316-666
615-637	PF00096	Zinc finger, C2H2 type	overlaps 316-666
643-665	PF00096	Zinc finger, C2H2 type	overlaps 316-666
671-693	PF00096	Zinc finger, C2H2 type	overlaps 668-781
699-721	PF00096	Zinc finger, C2H2 type	overlaps 668-781
727-749	PF00096	Zinc finger, C2H2 type	overlaps 668-781
755-777	PF00096	Zinc finger, C2H2 type	overlaps 668-781