ModCRE DB

Transcription factor

Q9P243 - ZFAT

Zinc finger protein ZFAT (Zinc finger gene in AITD susceptibility region) (Zinc finger protein 406)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 1243 aa

14 Generated PWM 16 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)1
MotifPredictionSourceDNA bindingSupportLogoActions
M07842_2.00 NN 70-40% CisBP CTCACCTG 61.7% identity Open · Scan
ModCRE13
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q9P243_ZFAT_HUMAN:404:479_2kmk_A_1 ModCRE Homology model CGGGCACCCGCACCGC Region 404-479 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:409:478_1a1g_A_1 ModCRE Homology model ACCCCCAACC Region 409-478 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:409:478_1a1i_A_1 ModCRE Homology model CCGCCCCACC Region 409-478 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:409:478_1a1j_A_1 ModCRE Homology model CCGACCAACC Region 409-478 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:409:478_1a1k_A_1 ModCRE Homology model CTGAGGACAC Region 409-478 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:743:793_3uk3_C_1 ModCRE Homology model AAGGGATCAAA Region 743-793 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:743:793_3uk3_D_1 ModCRE Homology model TGCACTCCAT Region 743-793 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:743:793_4is1_C_1 ModCRE Homology model AAGGGATGAAA Region 743-793 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:743:793_4is1_D_1 ModCRE Homology model TGTGCCCGAG Region 743-793 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:747:822_5keb_A_1 ModCRE Homology model CAAGGTCTCG Region 747-822 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:805:990_8sss_A_1 ModCRE Homology model GGGGCGCCTCCGGGGCCCCCAGA Region 805-990 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:805:990_8sst_A_1 ModCRE Homology model CCCGCGGGGCGGGCCCCCCGAGG Region 805-990 · 1 3D model Open · Scan
TFS_sp_Q9P243_ZFAT_HUMAN:877:991_5t0u_A_1 ModCRE Homology model AACACTCGGGCCTTGCGG Region 877-991 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1243 aa
404-479
743-1021

Region 404-479 5 PWM

Residues
76 aa
Domains
No overlapping PFAM annotation recorded
3D models
5 active PDBs
Templates
1A1G, 1A1I, 1A1J, 1A1K, 2KMK
Sources
Predicted = Low
Scan this region Show models

Region 743-1021 8 PWM

Residues
279 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
11 active PDBs · 6 summary rows
Templates
1LLM, 3UK3, 4IS1, 5KEB, 5T0U, 7W1M, 8SSR, 8SSS, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
16 active PDB models 6 summary rows
Region 404-4795 models
Actions
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:404:479_2kmk_A_1 2kmk 404-479 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:409:478_1a1g_A_1 1a1g 409-478 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:409:478_1a1i_A_1 1a1i 409-478 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:409:478_1a1j_A_1 1a1j 409-478 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:409:478_1a1k_A_1 1a1k 409-478 View model · PDB
Region 743-102111 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q9P243_ZFAT_HUMAN:906:956_1llm_C_1 1llm 906-956 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:743:793_3uk3_C_1 3uk3 743-793 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:743:793_3uk3_D_1 3uk3 743-793 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:743:793_4is1_C_1 4is1 743-793 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:743:793_4is1_D_1 4is1 743-793 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:743:986_8ssr_A_1 8ssr 743-986 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:747:822_5keb_A_1 5keb 747-822 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:805:1021_7w1m_H_1 7w1m 805-1021 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:805:990_8sss_A_1 8sss 805-990 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:805:990_8sst_A_1 8sst 805-990 View model · PDB
Predicted = Low TFS_sp_Q9P243_ZFAT_HUMAN:877:991_5t0u_A_1 5t0u 877-991 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 5t0u 743:1021 877 991 P:A · DNA:B,C 41.4% / 56.0% 67 View · PDB TFS_sp_Q9P243_ZFAT_HUMAN:877:991_5t0u_A_1
1 1llm 743:1021 906,906 956,956 P:C,D · DNA:A,B 35.3% / 52.9% 58,60 View · PDB DIMER_sp_Q9P243_ZFAT_HUMAN:906:956_1llm_C_1
1 8sst 743:1021 805 990 P:A · DNA:B,C 34.5% / 52.1% 92 View · PDB TFS_sp_Q9P243_ZFAT_HUMAN:805:990_8sst_A_1
2 8sss 743:1021 805 990 P:A · DNA:B,C 34.5% / 52.1% 92 View · PDB TFS_sp_Q9P243_ZFAT_HUMAN:805:990_8sss_A_1
3 7w1m 743:1021 805 1021 P:H · DNA:F,G 32.6% / 51.5% 66 View · PDB TFS_sp_Q9P243_ZFAT_HUMAN:805:1021_7w1m_H_1
5 8ssr 743:1021 743 986 P:A · DNA:B,C 29.1% / 45.0% 91 View · PDB TFS_sp_Q9P243_ZFAT_HUMAN:743:986_8ssr_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
271-293PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
299-322PF13909C2H2-type zinc-finger domainNo overlap with loaded model regions
909-931PF00096Zinc finger, C2H2 typeoverlaps 743-1021
939-959PF00096Zinc finger, C2H2 typeoverlaps 743-1021