ModCRE DB

Transcription factor

Q9UJU2 - LEF1

Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 399 aa

13 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known13
MotifPredictionSourceDNA bindingSupportLogoActions
MA0768.1 Known JASPAR AAAGATCAAAGGGTT Direct PWM Open · Scan
M03511_2.00 Known CisBP AAAGATCAAAGGGTT Direct PWM Open · Scan
M05771_2.00 Known CisBP ACATCAAAG Direct PWM Open · Scan
M05772_2.00 Known CisBP ACATCGGGGCGCTGA Direct PWM Open · Scan
M05773_2.00 Known CisBP ACATCAAAG Direct PWM Open · Scan
M05774_2.00 Known CisBP ACATCGGGGCGCTGA Direct PWM Open · Scan
M05775_2.00 Known CisBP AGATCAAAG Direct PWM Open · Scan
M05776_2.00 Known CisBP ACATCGGGGCGCTGA Direct PWM Open · Scan
M05777_2.00 Known CisBP AGATCAAAG Direct PWM Open · Scan
M05778_2.00 Known CisBP ACATCGGGGCGCTGA Direct PWM Open · Scan
M05895_2.00 Known CisBP ATCAAAGGAA Direct PWM Open · Scan
M09392_2.00 Known CisBP TCCTTTGATTTGCT Direct PWM Open · Scan
LEF1_HUMAN.H11MO.0.A Known HOCOMOCO TCCTTTGATTTGCT Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 399 aa
297-366

Region 297-366 0 PWM

Residues
70 aa
Domains
PF00505 · HMG (high mobility group) box
3D models
1 active PDB
Templates
4S2Q
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 297-3661 model
Actions
Predicted = Low TFS_Q9UJU2:297:366_4s2q_D_1 4s2q 297-366 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
9-213PF08347N-terminal CTNNB1 bindingNo overlap with loaded model regions
299-367PF00505HMG (high mobility group) boxoverlaps 297-366