Region 44-358 2 PWM
- Residues
- 315 aa
- Domains
- PF18104 · Jumonji domain-containing protein 2A Tudor domain PF00628 · PHD-finger PF30898 · Polycomb-like middle domain
- 3D models
- 3 active PDBs · 3 summary rows
- Templates
- 5XFQ, 5XFR
- Sources
- Predicted = Low
Transcription factor
Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2) (Metal-response element DNA-binding protein M96) (Polycomb-like protein 2) (hPCl2)
Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 593 aa
Only entries with a generated matrix are shown here.
| Motif | Prediction | Source | DNA binding | Support | Logo | Actions |
|---|---|---|---|---|---|---|
| M00968_2.00 | Known | CisBP | AACCCGACGGC | Direct PWM | Open · Scan |
No generated PWM in this category.
No generated PWM in this category.
| Motif | Prediction | Source | DNA binding | Support | Logo | Actions |
|---|---|---|---|---|---|---|
| TFS_sp_Q9Y483_MTF2_HUMAN:45:358_5xfr_B_1 | ModCRE | Homology model | GCCCCCCCG | Region 45-358 · 1 3D model | Open · Scan | |
| TFS_sp_Q9Y483_MTF2_HUMAN:48:352_5xfq_A_1 | ModCRE | Homology model | CCCCCGGAA | Region 48-352 · 1 3D model | Open · Scan |
Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.
| Actions | ||||
|---|---|---|---|---|
| Predicted = Low | TFS_sp_Q9Y483_MTF2_HUMAN:44:357_5xfr_A_1 | 5xfr | 44-357 | View model · PDB |
| Predicted = Low | TFS_sp_Q9Y483_MTF2_HUMAN:45:358_5xfr_B_1 | 5xfr | 45-358 | View model · PDB |
| Predicted = Low | TFS_sp_Q9Y483_MTF2_HUMAN:48:352_5xfq_A_1 | 5xfq | 48-352 | View model · PDB |
Model-summary evidence imported for this region.
| Rank | Template | Domain | N-tails | C-tails | Chains | Identity / similarity | Coverage | Model file |
|---|---|---|---|---|---|---|---|---|
| 1 | 5xfr | 44:358 | 44 | 357 | P:A · DNA:E,F | 98.1% / 98.1% | 100 | View · PDB TFS_sp_Q9Y483_MTF2_HUMAN:44:357_5xfr_A_1 |
| 2 | 5xfr | 44:358 | 45 | 358 | P:B · DNA:E,F | 94.6% / 94.6% | 100 | View · PDB TFS_sp_Q9Y483_MTF2_HUMAN:45:358_5xfr_B_1 |
| 3 | 5xfq | 44:358 | 48 | 352 | P:A · DNA:C,D | 58.0% / 71.1% | 97 | View · PDB TFS_sp_Q9Y483_MTF2_HUMAN:48:352_5xfq_A_1 |
View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.
Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.
| Residues | PFAM | Domain | Used by prediction region? |
|---|---|---|---|
| 49-84 | PF18104 | Jumonji domain-containing protein 2A Tudor domain | overlaps 44-358 |
| 105-154 | PF00628 | PHD-finger | overlaps 44-358 |
| 267-347 | PF30898 | Polycomb-like middle domain | overlaps 44-358 |
| 544-591 | PF14061 | Polycomb-like MTF2 factor 2 | No overlap with loaded model regions |