ModCRE DB

Transcription factor

Q9Y483 - MTF2

Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2) (Metal-response element DNA-binding protein M96) (Polycomb-like protein 2) (hPCl2)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 593 aa

3 Generated PWM 3 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M00968_2.00 Known CisBP AACCCGACGGC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE2
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q9Y483_MTF2_HUMAN:45:358_5xfr_B_1 ModCRE Homology model GCCCCCCCG Region 45-358 · 1 3D model Open · Scan
TFS_sp_Q9Y483_MTF2_HUMAN:48:352_5xfq_A_1 ModCRE Homology model CCCCCGGAA Region 48-352 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 593 aa
44-358

Region 44-358 2 PWM

Residues
315 aa
Domains
PF18104 · Jumonji domain-containing protein 2A Tudor domain PF00628 · PHD-finger PF30898 · Polycomb-like middle domain
3D models
3 active PDBs · 3 summary rows
Templates
5XFQ, 5XFR
Sources
Predicted = Low
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
3 active PDB models 3 summary rows
Region 44-3583 models · 3 summary rows
Actions
Predicted = Low TFS_sp_Q9Y483_MTF2_HUMAN:44:357_5xfr_A_1 5xfr 44-357 View model · PDB
Predicted = Low TFS_sp_Q9Y483_MTF2_HUMAN:45:358_5xfr_B_1 5xfr 45-358 View model · PDB
Predicted = Low TFS_sp_Q9Y483_MTF2_HUMAN:48:352_5xfq_A_1 5xfq 48-352 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5xfr 44:358 44 357 P:A · DNA:E,F 98.1% / 98.1% 100 View · PDB TFS_sp_Q9Y483_MTF2_HUMAN:44:357_5xfr_A_1
2 5xfr 44:358 45 358 P:B · DNA:E,F 94.6% / 94.6% 100 View · PDB TFS_sp_Q9Y483_MTF2_HUMAN:45:358_5xfr_B_1
3 5xfq 44:358 48 352 P:A · DNA:C,D 58.0% / 71.1% 97 View · PDB TFS_sp_Q9Y483_MTF2_HUMAN:48:352_5xfq_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
49-84PF18104Jumonji domain-containing protein 2A Tudor domainoverlaps 44-358
105-154PF00628PHD-fingeroverlaps 44-358
267-347PF30898Polycomb-like middle domainoverlaps 44-358
544-591PF14061Polycomb-like MTF2 factor 2No overlap with loaded model regions