ModCRE DB

Transcription factor

Q9Y543 - HES2

Transcription factor HES-2 (Class B basic helix-loop-helix protein 40) (bHLHb40) (Hairy and enhancer of split 2)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 173 aa

4 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known4
MotifPredictionSourceDNA bindingSupportLogoActions
MA0616.2 Known JASPAR GGCACGTGCC Direct PWM Open · Scan
MA0616.3 Known JASPAR GGCACGTGC Direct PWM Open · Scan
M04060_2.00 Known CisBP GGCACGTGCC Direct PWM Open · Scan
M04061_2.00 Known CisBP CCCACGTACC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 173 aa
21-70

Region 21-70 0 PWM

Residues
50 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
1 active PDB
Templates
1AM9
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 21-701 model
Actions
Predicted = Low DIMER_Q9Y543:21:70_1am9_B_1 1am9 21-70 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
14-70PF00010Helix-loop-helix DNA-binding domainoverlaps 21-70
85-123PF07527Hairy OrangeNo overlap with loaded model regions