ModCRE DB

Transcription factor

Q9Y6X8 - ZHX2

Zinc fingers and homeoboxes protein 2 (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP) (Zinc finger and homeodomain protein 2)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 837 aa

11 Generated PWM 16 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE11
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q9Y6X8_ZHX2_HUMAN:275:316_1du0_A_1 ModCRE Homology model CCACAAAATGAGCAAA Region 275-316 · 1 3D model Open · Scan
DIMER_sp_Q9Y6X8_ZHX2_HUMAN:275:317_5z2t_D_1 ModCRE Homology model CAAATTTTATCCG Region 275-317 · 1 3D model Open · Scan
DIMER_sp_Q9Y6X8_ZHX2_HUMAN:275:317_6a8r_B_1 ModCRE Homology model AAATTTTGCG Region 275-317 · 1 3D model Open · Scan
DIMER_sp_Q9Y6X8_ZHX2_HUMAN:275:317_6dfy_C_1 ModCRE Homology model AATTTTATTTT Region 275-317 · 1 3D model Open · Scan
DIMER_sp_Q9Y6X8_ZHX2_HUMAN:281:316_1jgg_B_1 ModCRE Homology model TAATGCAGTC Region 281-316 · 1 3D model Open · Scan
TFS_sp_Q9Y6X8_ZHX2_HUMAN:429:493_6u82_A_1 ModCRE Homology model TTGATTTTTTT Region 429-493 · 1 3D model Open · Scan
TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5z6z_A_1 ModCRE Homology model AATAAAATCTTTTTAATA Region 447-493 · 1 3D model Open · Scan
TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5zfw_A_1 ModCRE Homology model TATAAAATTATTTAAATA Region 447-493 · 1 3D model Open · Scan
TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5zfy_A_1 ModCRE Homology model AAAAAAATGATTTTCTTA Region 447-493 · 1 3D model Open · Scan
TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5zfz_A_1 ModCRE Homology model AATAAAATTAGTTTAAGT Region 447-493 · 1 3D model Open · Scan
TFS_sp_Q9Y6X8_ZHX2_HUMAN:537:582_1apl_D_1 ModCRE Homology model TTTAAAATTTGG Region 537-582 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 837 aa
275-317
429-687

Region 275-317 5 PWM

Residues
43 aa
Domains
No overlapping PFAM annotation recorded
3D models
5 active PDBs
Templates
1DU0, 1JGG, 5Z2T, 6A8R, 6DFY
Sources
Predicted = Low
Scan this region Show models

Region 429-687 6 PWM

Residues
259 aa
Domains
PF00046 · Homeodomain PF00046 · Homeodomain PF00046 · Homeodomain
3D models
11 active PDBs · 10 summary rows
Templates
1APL, 1FJL, 2HDD, 2HOS, 2HOT, 3A01, 5Z6Z, 5ZFW, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
16 active PDB models 10 summary rows
Region 275-3175 models
Actions
Predicted = Low DIMER_sp_Q9Y6X8_ZHX2_HUMAN:275:316_1du0_A_1 1du0 275-316 View model · PDB
Predicted = Low DIMER_sp_Q9Y6X8_ZHX2_HUMAN:275:317_5z2t_D_1 5z2t 275-317 View model · PDB
Predicted = Low DIMER_sp_Q9Y6X8_ZHX2_HUMAN:275:317_6a8r_B_1 6a8r 275-317 View model · PDB
Predicted = Low DIMER_sp_Q9Y6X8_ZHX2_HUMAN:275:317_6dfy_C_1 6dfy 275-317 View model · PDB
Predicted = Low DIMER_sp_Q9Y6X8_ZHX2_HUMAN:281:316_1jgg_B_1 1jgg 281-316 View model · PDB
Region 429-68711 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q9Y6X8_ZHX2_HUMAN:631:684_2hdd_B_1 2hdd 631-684 View model · PDB
Predicted = Low DIMER_sp_Q9Y6X8_ZHX2_HUMAN:631:684_2hos_B_1 2hos 631-684 View model · PDB
Predicted = Low DIMER_sp_Q9Y6X8_ZHX2_HUMAN:631:684_2hot_B_1 2hot 631-684 View model · PDB
Predicted = Low DIMER_sp_Q9Y6X8_ZHX2_HUMAN:636:684_1fjl_B_1 1fjl 636-684 View model · PDB
Predicted = Low DIMER_sp_Q9Y6X8_ZHX2_HUMAN:639:680_3a01_B_1 3a01 639-680 View model · PDB
Predicted = Low TFS_sp_Q9Y6X8_ZHX2_HUMAN:429:493_6u82_A_1 6u82 429-493 View model · PDB
Predicted = Low TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5z6z_A_1 5z6z 447-493 View model · PDB
Predicted = Low TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5zfw_A_1 5zfw 447-493 View model · PDB
Predicted = Low TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5zfy_A_1 5zfy 447-493 View model · PDB
Predicted = Low TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5zfz_A_1 5zfz 447-493 View model · PDB
Predicted = Low TFS_sp_Q9Y6X8_ZHX2_HUMAN:537:582_1apl_D_1 1apl 537-582 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5zfz 429:505 447 493 P:A · DNA:D,E 38.3% / 48.9% 38 View · PDB TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5zfz_A_1
2 5zfw 429:505 447 493 P:A · DNA:D,E 38.3% / 48.9% 38 View · PDB TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5zfw_A_1
3 5z6z 429:505 447 493 P:A · DNA:D,E 38.3% / 48.9% 38 View · PDB TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5z6z_A_1
4 5zfy 429:505 447 493 P:A · DNA:D,E 38.3% / 48.9% 38 View · PDB TFS_sp_Q9Y6X8_ZHX2_HUMAN:447:493_5zfy_A_1
3 3a01 429:505 430,639 496,680 P:A,B · DNA:C,D 35.7% / 50.0% 85,73 View · PDB DIMER_sp_Q9Y6X8_ZHX2_HUMAN:639:680_3a01_B_1
2 1fjl 429:505 636,636 684,684 P:A,B · DNA:D,E 34.7% / 49.0% 75,85 View · PDB DIMER_sp_Q9Y6X8_ZHX2_HUMAN:636:684_1fjl_B_1
5 6u82 429:505 429 493 P:A · DNA:B 33.8% / 41.5% 49 View · PDB TFS_sp_Q9Y6X8_ZHX2_HUMAN:429:493_6u82_A_1
1 2hdd 429:505 634,631 684,684 P:A,B · DNA:C,D 33.3% / 51.9% 92,96 View · PDB DIMER_sp_Q9Y6X8_ZHX2_HUMAN:631:684_2hdd_B_1
4 2hot 429:505 634,631 687,684 P:A,B · DNA:C,D 31.5% / 51.9% 96,93 View · PDB DIMER_sp_Q9Y6X8_ZHX2_HUMAN:631:684_2hot_B_1
5 2hos 429:505 634,631 687,684 P:A,B · DNA:C,D 31.5% / 51.9% 96,93 View · PDB DIMER_sp_Q9Y6X8_ZHX2_HUMAN:631:684_2hos_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
107-157PF18387Zinc-fingers and homeoboxes C2H2 finger domainNo overlap with loaded model regions
447-495PF00046Homeodomainoverlaps 429-687
537-581PF00046Homeodomainoverlaps 429-687
636-681PF00046Homeodomainoverlaps 429-687