ModCRE DB

Transcription factor

X5D7M0 - NPAS3

Neuronal PAS domain-containing protein 3 (Basic-helix-loop-helix-PAS protein MOP6) (Member of PAS protein 6)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 900 aa

8 Generated PWM 8 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE8
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_X5D7M0_X5D7M0_HUMAN:124:380_8osl_N_1 ModCRE Homology model GCGCGGGTCCGACGCGC Region 124-380 · 1 3D model Open · Scan
DIMER_tr_X5D7M0_X5D7M0_HUMAN:21:417_4zpk_B_1 ModCRE Homology model CCGTACACCGCGCCC Region 21-417 · 1 3D model Open · Scan
DIMER_tr_X5D7M0_X5D7M0_HUMAN:22:404_4zpr_B_1 ModCRE Homology model GCGCGTACCCGCGGGGG Region 22-404 · 1 3D model Open · Scan
DIMER_tr_X5D7M0_X5D7M0_HUMAN:22:418_5sy7_B_1 ModCRE Homology model CCGCACACGCGCCGGGGG Region 22-418 · 1 3D model Open · Scan
TFS_tr_X5D7M0_X5D7M0_HUMAN:124:380_8osl_N_1 ModCRE Homology model CCGCGTCGGACCAGCGC Region 124-380 · 1 3D model Open · Scan
TFS_tr_X5D7M0_X5D7M0_HUMAN:21:417_4zpk_B_1 ModCRE Homology model CCGTACACCGCGCCC Region 21-417 · 1 3D model Open · Scan
TFS_tr_X5D7M0_X5D7M0_HUMAN:22:404_4zpr_B_1 ModCRE Homology model GCGCGTACCCGCGGGGG Region 22-404 · 1 3D model Open · Scan
TFS_tr_X5D7M0_X5D7M0_HUMAN:22:418_5sy7_B_1 ModCRE Homology model GCGCGCACGCGCCGGGGC Region 22-418 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 900 aa
21-418

Region 21-418 8 PWM

Residues
398 aa
Domains
PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain PF00989 · PAS fold PF08447 · PAS fold
3D models
8 active PDBs · 8 summary rows
Templates
4ZPK, 4ZPR, 5SY7, 8OSL
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
8 active PDB models 8 summary rows
Region 21-4188 models · 8 summary rows
Actions
Predicted = Low DIMER_tr_X5D7M0_X5D7M0_HUMAN:124:380_8osl_N_1 8osl 124-380 View model · PDB
Predicted = Low DIMER_tr_X5D7M0_X5D7M0_HUMAN:21:417_4zpk_B_1 4zpk 21-417 View model · PDB
Predicted = Low DIMER_tr_X5D7M0_X5D7M0_HUMAN:22:404_4zpr_B_1 4zpr 22-404 View model · PDB
Predicted = Low DIMER_tr_X5D7M0_X5D7M0_HUMAN:22:418_5sy7_B_1 5sy7 22-418 View model · PDB
Predicted = Low TFS_tr_X5D7M0_X5D7M0_HUMAN:124:380_8osl_N_1 8osl 124-380 View model · PDB
Predicted = Low TFS_tr_X5D7M0_X5D7M0_HUMAN:21:417_4zpk_B_1 4zpk 21-417 View model · PDB
Predicted = Low TFS_tr_X5D7M0_X5D7M0_HUMAN:22:404_4zpr_B_1 4zpr 22-404 View model · PDB
Predicted = Low TFS_tr_X5D7M0_X5D7M0_HUMAN:22:418_5sy7_B_1 5sy7 22-418 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5sy7 21:418 124,22 180,418 P:A,B · DNA:C,D 69.5% / 69.5% 20,100 View · PDB TFS_tr_X5D7M0_X5D7M0_HUMAN:22:418_5sy7_B_1
1 5sy7 21:418 124,22 180,418 P:A,B · DNA:C,D 69.5% / 69.5% 20,100 View · PDB DIMER_tr_X5D7M0_X5D7M0_HUMAN:22:418_5sy7_B_1
3 4zpr 21:418 124,22 180,404 P:A,B · DNA:C,D 34.0% / 49.2% 23,96 View · PDB TFS_tr_X5D7M0_X5D7M0_HUMAN:22:404_4zpr_B_1
3 4zpr 21:418 124,22 180,404 P:A,B · DNA:C,D 34.0% / 49.2% 23,96 View · PDB DIMER_tr_X5D7M0_X5D7M0_HUMAN:22:404_4zpr_B_1
2 4zpk 21:418 124,21 180,417 P:A,B · DNA:C,D 32.0% / 50.4% 21,96 View · PDB TFS_tr_X5D7M0_X5D7M0_HUMAN:21:417_4zpk_B_1
2 4zpk 21:418 124,21 180,417 P:A,B · DNA:C,D 32.0% / 50.4% 21,96 View · PDB DIMER_tr_X5D7M0_X5D7M0_HUMAN:21:417_4zpk_B_1
4 8osl 21:418 124,23 380,71 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB TFS_tr_X5D7M0_X5D7M0_HUMAN:124:380_8osl_N_1
4 8osl 21:418 124,23 380,71 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB DIMER_tr_X5D7M0_X5D7M0_HUMAN:124:380_8osl_N_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
22-81PF23171Hypoxia-inducible factor 1-alpha bHLH domainoverlaps 21-418
122-182PF00989PAS foldoverlaps 21-418
313-400PF08447PAS foldoverlaps 21-418