ModCRE DB

Transcription factor

X5D9I7 - NPAS3

Neuronal PAS domain-containing protein 3 (Basic-helix-loop-helix-PAS protein MOP6) (Member of PAS protein 6)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 795 aa

8 Generated PWM 8 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE8
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_X5D9I7_X5D9I7_HUMAN:141:397_8osl_N_1 ModCRE Homology model GCGCGGGTCCGACGCGT Region 141-397 · 1 3D model Open · Scan
DIMER_tr_X5D9I7_X5D9I7_HUMAN:142:421_4zpr_B_1 ModCRE Homology model GGGGGGCGGGGGC Region 142-421 · 1 3D model Open · Scan
DIMER_tr_X5D9I7_X5D9I7_HUMAN:142:434_4zpk_B_1 ModCRE Homology model GGGGCGCCGGTTTT Region 142-434 · 1 3D model Open · Scan
DIMER_tr_X5D9I7_X5D9I7_HUMAN:22:435_5sy7_B_1 ModCRE Homology model CCCCGGCGCGGTGTACAC Region 22-435 · 1 3D model Open · Scan
TFS_tr_X5D9I7_X5D9I7_HUMAN:141:397_8osl_N_1 ModCRE Homology model GCGCGGGTCCGACGCGG Region 141-397 · 1 3D model Open · Scan
TFS_tr_X5D9I7_X5D9I7_HUMAN:142:421_4zpr_B_1 ModCRE Homology model GGGGGGCGGGGGA Region 142-421 · 1 3D model Open · Scan
TFS_tr_X5D9I7_X5D9I7_HUMAN:142:434_4zpk_B_1 ModCRE Homology model GGGGCGCCGGTTAT Region 142-434 · 1 3D model Open · Scan
TFS_tr_X5D9I7_X5D9I7_HUMAN:22:435_5sy7_B_1 ModCRE Homology model CCCCGGCGCGGTGTACGC Region 22-435 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 795 aa
22-435

Region 22-435 8 PWM

Residues
414 aa
Domains
PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain PF00989 · PAS fold PF08447 · PAS fold
3D models
8 active PDBs · 8 summary rows
Templates
4ZPK, 4ZPR, 5SY7, 8OSL
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
8 active PDB models 8 summary rows
Region 22-4358 models · 8 summary rows
Actions
Predicted = Low DIMER_tr_X5D9I7_X5D9I7_HUMAN:141:397_8osl_N_1 8osl 141-397 View model · PDB
Predicted = Low DIMER_tr_X5D9I7_X5D9I7_HUMAN:142:421_4zpr_B_1 4zpr 142-421 View model · PDB
Predicted = Low DIMER_tr_X5D9I7_X5D9I7_HUMAN:142:434_4zpk_B_1 4zpk 142-434 View model · PDB
Predicted = Low DIMER_tr_X5D9I7_X5D9I7_HUMAN:22:435_5sy7_B_1 5sy7 22-435 View model · PDB
Predicted = Low TFS_tr_X5D9I7_X5D9I7_HUMAN:141:397_8osl_N_1 8osl 141-397 View model · PDB
Predicted = Low TFS_tr_X5D9I7_X5D9I7_HUMAN:142:421_4zpr_B_1 4zpr 142-421 View model · PDB
Predicted = Low TFS_tr_X5D9I7_X5D9I7_HUMAN:142:434_4zpk_B_1 4zpk 142-434 View model · PDB
Predicted = Low TFS_tr_X5D9I7_X5D9I7_HUMAN:22:435_5sy7_B_1 5sy7 22-435 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5sy7 22:435 141,22 197,435 P:A,B · DNA:C,D 66.7% / 66.7% 20,100 View · PDB TFS_tr_X5D9I7_X5D9I7_HUMAN:22:435_5sy7_B_1
1 5sy7 22:435 141,22 197,435 P:A,B · DNA:C,D 66.7% / 66.7% 20,100 View · PDB DIMER_tr_X5D9I7_X5D9I7_HUMAN:22:435_5sy7_B_1
3 4zpr 22:435 141,142 197,421 P:A,B · DNA:C,D 32.6% / 50.2% 23,74 View · PDB TFS_tr_X5D9I7_X5D9I7_HUMAN:142:421_4zpr_B_1
3 4zpr 22:435 141,142 197,421 P:A,B · DNA:C,D 32.6% / 50.2% 23,74 View · PDB DIMER_tr_X5D9I7_X5D9I7_HUMAN:142:421_4zpr_B_1
2 4zpk 22:435 141,142 197,434 P:A,B · DNA:C,D 30.8% / 51.2% 21,71 View · PDB TFS_tr_X5D9I7_X5D9I7_HUMAN:142:434_4zpk_B_1
2 4zpk 22:435 141,142 197,434 P:A,B · DNA:C,D 30.8% / 51.2% 21,71 View · PDB DIMER_tr_X5D9I7_X5D9I7_HUMAN:142:434_4zpk_B_1
4 8osl 22:435 141,23 397,71 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB TFS_tr_X5D9I7_X5D9I7_HUMAN:141:397_8osl_N_1
4 8osl 22:435 141,23 397,71 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB DIMER_tr_X5D9I7_X5D9I7_HUMAN:141:397_8osl_N_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
22-81PF23171Hypoxia-inducible factor 1-alpha bHLH domainoverlaps 22-435
139-199PF00989PAS foldoverlaps 22-435
330-417PF08447PAS foldoverlaps 22-435