ModCRE DB

Transcription factor

X5DNV7 - NPAS3

Neuronal PAS domain-containing protein 3 (Basic-helix-loop-helix-PAS protein MOP6) (Member of PAS protein 6)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 901 aa

8 Generated PWM 8 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE8
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_X5DNV7_X5DNV7_HUMAN:122:378_8osl_N_1 ModCRE Homology model GCGCGGGTCCGACGCGG Region 122-378 · 1 3D model Open · Scan
DIMER_tr_X5DNV7_X5DNV7_HUMAN:21:415_4zpk_B_1 ModCRE Homology model CCCGGCGGGGTACGC Region 21-415 · 1 3D model Open · Scan
DIMER_tr_X5DNV7_X5DNV7_HUMAN:22:402_4zpr_B_1 ModCRE Homology model CCCCCGCGCGTACGCAC Region 22-402 · 1 3D model Open · Scan
DIMER_tr_X5DNV7_X5DNV7_HUMAN:22:416_5sy7_B_1 ModCRE Homology model CCCCCGGGCGGTGCGCGC Region 22-416 · 1 3D model Open · Scan
TFS_tr_X5DNV7_X5DNV7_HUMAN:122:378_8osl_N_1 ModCRE Homology model GCGCGGGTCCGACGCGC Region 122-378 · 1 3D model Open · Scan
TFS_tr_X5DNV7_X5DNV7_HUMAN:21:415_4zpk_B_1 ModCRE Homology model GCGTACACCGCCGGG Region 21-415 · 1 3D model Open · Scan
TFS_tr_X5DNV7_X5DNV7_HUMAN:22:402_4zpr_B_1 ModCRE Homology model GCGCGTACGCGCGGGGG Region 22-402 · 1 3D model Open · Scan
TFS_tr_X5DNV7_X5DNV7_HUMAN:22:416_5sy7_B_1 ModCRE Homology model GCGCGCACGGCCCGGGGC Region 22-416 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 901 aa
21-416

Region 21-416 8 PWM

Residues
396 aa
Domains
PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain PF00989 · PAS fold PF08447 · PAS fold
3D models
8 active PDBs · 8 summary rows
Templates
4ZPK, 4ZPR, 5SY7, 8OSL
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
8 active PDB models 8 summary rows
Region 21-4168 models · 8 summary rows
Actions
Predicted = Low DIMER_tr_X5DNV7_X5DNV7_HUMAN:122:378_8osl_N_1 8osl 122-378 View model · PDB
Predicted = Low DIMER_tr_X5DNV7_X5DNV7_HUMAN:21:415_4zpk_B_1 4zpk 21-415 View model · PDB
Predicted = Low DIMER_tr_X5DNV7_X5DNV7_HUMAN:22:402_4zpr_B_1 4zpr 22-402 View model · PDB
Predicted = Low DIMER_tr_X5DNV7_X5DNV7_HUMAN:22:416_5sy7_B_1 5sy7 22-416 View model · PDB
Predicted = Low TFS_tr_X5DNV7_X5DNV7_HUMAN:122:378_8osl_N_1 8osl 122-378 View model · PDB
Predicted = Low TFS_tr_X5DNV7_X5DNV7_HUMAN:21:415_4zpk_B_1 4zpk 21-415 View model · PDB
Predicted = Low TFS_tr_X5DNV7_X5DNV7_HUMAN:22:402_4zpr_B_1 4zpr 22-402 View model · PDB
Predicted = Low TFS_tr_X5DNV7_X5DNV7_HUMAN:22:416_5sy7_B_1 5sy7 22-416 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5sy7 21:416 122,22 178,416 P:A,B · DNA:C,D 69.9% / 69.9% 20,100 View · PDB TFS_tr_X5DNV7_X5DNV7_HUMAN:22:416_5sy7_B_1
1 5sy7 21:416 122,22 178,416 P:A,B · DNA:C,D 69.9% / 69.9% 20,100 View · PDB DIMER_tr_X5DNV7_X5DNV7_HUMAN:22:416_5sy7_B_1
3 4zpr 21:416 122,22 178,402 P:A,B · DNA:C,D 33.9% / 48.7% 23,96 View · PDB TFS_tr_X5DNV7_X5DNV7_HUMAN:22:402_4zpr_B_1
3 4zpr 21:416 122,22 178,402 P:A,B · DNA:C,D 33.9% / 48.7% 23,96 View · PDB DIMER_tr_X5DNV7_X5DNV7_HUMAN:22:402_4zpr_B_1
2 4zpk 21:416 122,21 178,415 P:A,B · DNA:C,D 32.4% / 50.6% 21,96 View · PDB TFS_tr_X5DNV7_X5DNV7_HUMAN:21:415_4zpk_B_1
2 4zpk 21:416 122,21 178,415 P:A,B · DNA:C,D 32.4% / 50.6% 21,96 View · PDB DIMER_tr_X5DNV7_X5DNV7_HUMAN:21:415_4zpk_B_1
4 8osl 21:416 122,23 378,71 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB TFS_tr_X5DNV7_X5DNV7_HUMAN:122:378_8osl_N_1
4 8osl 21:416 122,23 378,71 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB DIMER_tr_X5DNV7_X5DNV7_HUMAN:122:378_8osl_N_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
22-81PF23171Hypoxia-inducible factor 1-alpha bHLH domainoverlaps 21-416
120-180PF00989PAS foldoverlaps 21-416
311-398PF08447PAS foldoverlaps 21-416