ModCRE DB

Transcription factor

X5DR67 - NPAS3

Neuronal PAS domain-containing protein 3 (Basic-helix-loop-helix-PAS protein MOP6) (Member of PAS protein 6)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 918 aa

8 Generated PWM 8 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE8
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_X5DR67_X5DR67_HUMAN:139:395_8osl_N_1 ModCRE Homology model CCGCGTCGGACCATCGC Region 139-395 · 1 3D model Open · Scan
DIMER_tr_X5DR67_X5DR67_HUMAN:140:419_4zpr_B_1 ModCRE Homology model GCCCCCGCCCCCC Region 140-419 · 1 3D model Open · Scan
DIMER_tr_X5DR67_X5DR67_HUMAN:140:432_4zpk_B_1 ModCRE Homology model CTATCCGGCGCCCC Region 140-432 · 1 3D model Open · Scan
DIMER_tr_X5DR67_X5DR67_HUMAN:22:433_5sy7_B_1 ModCRE Homology model GCGTACACGGCGCGGGGG Region 22-433 · 1 3D model Open · Scan
TFS_tr_X5DR67_X5DR67_HUMAN:139:395_8osl_N_1 ModCRE Homology model CCGCGTCGGACCAGCGC Region 139-395 · 1 3D model Open · Scan
TFS_tr_X5DR67_X5DR67_HUMAN:140:419_4zpr_B_1 ModCRE Homology model TCCCCCGCCCCCC Region 140-419 · 1 3D model Open · Scan
TFS_tr_X5DR67_X5DR67_HUMAN:140:432_4zpk_B_1 ModCRE Homology model AATTCCGGCGCCCC Region 140-432 · 1 3D model Open · Scan
TFS_tr_X5DR67_X5DR67_HUMAN:22:433_5sy7_B_1 ModCRE Homology model GCGTACACGGCGCGGGGG Region 22-433 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 918 aa
22-433

Region 22-433 8 PWM

Residues
412 aa
Domains
PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain PF00989 · PAS fold PF08447 · PAS fold
3D models
8 active PDBs · 8 summary rows
Templates
4ZPK, 4ZPR, 5SY7, 8OSL
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
8 active PDB models 8 summary rows
Region 22-4338 models · 8 summary rows
Actions
Predicted = Low DIMER_tr_X5DR67_X5DR67_HUMAN:139:395_8osl_N_1 8osl 139-395 View model · PDB
Predicted = Low DIMER_tr_X5DR67_X5DR67_HUMAN:140:419_4zpr_B_1 4zpr 140-419 View model · PDB
Predicted = Low DIMER_tr_X5DR67_X5DR67_HUMAN:140:432_4zpk_B_1 4zpk 140-432 View model · PDB
Predicted = Low DIMER_tr_X5DR67_X5DR67_HUMAN:22:433_5sy7_B_1 5sy7 22-433 View model · PDB
Predicted = Low TFS_tr_X5DR67_X5DR67_HUMAN:139:395_8osl_N_1 8osl 139-395 View model · PDB
Predicted = Low TFS_tr_X5DR67_X5DR67_HUMAN:140:419_4zpr_B_1 4zpr 140-419 View model · PDB
Predicted = Low TFS_tr_X5DR67_X5DR67_HUMAN:140:432_4zpk_B_1 4zpk 140-432 View model · PDB
Predicted = Low TFS_tr_X5DR67_X5DR67_HUMAN:22:433_5sy7_B_1 5sy7 22-433 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5sy7 22:433 139,22 195,433 P:A,B · DNA:C,D 67.0% / 67.0% 20,100 View · PDB TFS_tr_X5DR67_X5DR67_HUMAN:22:433_5sy7_B_1
1 5sy7 22:433 139,22 195,433 P:A,B · DNA:C,D 67.0% / 67.0% 20,100 View · PDB DIMER_tr_X5DR67_X5DR67_HUMAN:22:433_5sy7_B_1
3 4zpr 22:433 139,140 195,419 P:A,B · DNA:C,D 32.6% / 50.2% 23,74 View · PDB TFS_tr_X5DR67_X5DR67_HUMAN:140:419_4zpr_B_1
3 4zpr 22:433 139,140 195,419 P:A,B · DNA:C,D 32.6% / 50.2% 23,74 View · PDB DIMER_tr_X5DR67_X5DR67_HUMAN:140:419_4zpr_B_1
2 4zpk 22:433 139,140 195,432 P:A,B · DNA:C,D 30.8% / 51.2% 21,71 View · PDB TFS_tr_X5DR67_X5DR67_HUMAN:140:432_4zpk_B_1
2 4zpk 22:433 139,140 195,432 P:A,B · DNA:C,D 30.8% / 51.2% 21,71 View · PDB DIMER_tr_X5DR67_X5DR67_HUMAN:140:432_4zpk_B_1
4 8osl 22:433 139,23 395,71 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB TFS_tr_X5DR67_X5DR67_HUMAN:139:395_8osl_N_1
4 8osl 22:433 139,23 395,71 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB DIMER_tr_X5DR67_X5DR67_HUMAN:139:395_8osl_N_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
22-81PF23171Hypoxia-inducible factor 1-alpha bHLH domainoverlaps 22-433
137-197PF00989PAS foldoverlaps 22-433
328-415PF08447PAS foldoverlaps 22-433