ModCRE DB

Transcription factor

X5DRK2 - NPAS3

Neuronal PAS domain protein 3 isoform H

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 307 aa

4 Generated PWM 8 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE4
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_X5DRK2_X5DRK2_HUMAN:21:180_4zpk_B_1 ModCRE Homology model ACGCGTACGTGCGGG Region 21-180 · 1 3D model Open · Scan
TFS_tr_X5DRK2_X5DRK2_HUMAN:22:180_4zpr_B_1 ModCRE Homology model CTCCCACATGGGGCAAC Region 22-180 · 1 3D model Open · Scan
TFS_tr_X5DRK2_X5DRK2_HUMAN:22:306_5sy7_B_1 ModCRE Homology model GCATTTTTGTGTGACACA Region 22-306 · 1 3D model Open · Scan
TFS_tr_X5DRK2_X5DRK2_HUMAN:30:180_5nj8_A_1 ModCRE Homology model GTTTGGTGACAC Region 30-180 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 307 aa
21-306

Region 21-306 4 PWM

Residues
286 aa
Domains
PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain PF00989 · PAS fold
3D models
8 active PDBs · 8 summary rows
Templates
4ZPK, 4ZPR, 5NJ8, 5SY7
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
8 active PDB models 8 summary rows
Region 21-3068 models · 8 summary rows
Actions
Predicted = Low DIMER_tr_X5DRK2_X5DRK2_HUMAN:21:180_4zpk_B_1 4zpk 21-180 View model · PDB
Predicted = Low DIMER_tr_X5DRK2_X5DRK2_HUMAN:22:180_4zpr_B_1 4zpr 22-180 View model · PDB
Predicted = Low DIMER_tr_X5DRK2_X5DRK2_HUMAN:22:306_5sy7_B_1 5sy7 22-306 View model · PDB
Predicted = Low DIMER_tr_X5DRK2_X5DRK2_HUMAN:30:180_5nj8_A_1 5nj8 30-180 View model · PDB
Predicted = Low TFS_tr_X5DRK2_X5DRK2_HUMAN:21:180_4zpk_B_1 4zpk 21-180 View model · PDB
Predicted = Low TFS_tr_X5DRK2_X5DRK2_HUMAN:22:180_4zpr_B_1 4zpr 22-180 View model · PDB
Predicted = Low TFS_tr_X5DRK2_X5DRK2_HUMAN:22:306_5sy7_B_1 5sy7 22-306 View model · PDB
Predicted = Low TFS_tr_X5DRK2_X5DRK2_HUMAN:30:180_5nj8_A_1 5nj8 30-180 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5sy7 21:306 124,22 180,306 P:A,B · DNA:C,D 60.4% / 60.4% 20,62 View · PDB TFS_tr_X5DRK2_X5DRK2_HUMAN:22:306_5sy7_B_1
1 5sy7 21:306 124,22 180,306 P:A,B · DNA:C,D 60.4% / 60.4% 20,62 View · PDB DIMER_tr_X5DRK2_X5DRK2_HUMAN:22:306_5sy7_B_1
2 4zpr 21:306 124,22 180,180 P:A,B · DNA:C,D 44.7% / 56.0% 23,41 View · PDB TFS_tr_X5DRK2_X5DRK2_HUMAN:22:180_4zpr_B_1
2 4zpr 21:306 124,22 180,180 P:A,B · DNA:C,D 44.7% / 56.0% 23,41 View · PDB DIMER_tr_X5DRK2_X5DRK2_HUMAN:22:180_4zpr_B_1
3 4zpk 21:306 124,21 180,180 P:A,B · DNA:C,D 40.0% / 58.1% 21,41 View · PDB TFS_tr_X5DRK2_X5DRK2_HUMAN:21:180_4zpk_B_1
3 4zpk 21:306 124,21 180,180 P:A,B · DNA:C,D 40.0% / 58.1% 21,41 View · PDB DIMER_tr_X5DRK2_X5DRK2_HUMAN:21:180_4zpk_B_1
4 5nj8 21:306 30,124 180,180 P:A,B · DNA:E,F 27.2% / 47.0% 67,32 View · PDB TFS_tr_X5DRK2_X5DRK2_HUMAN:30:180_5nj8_A_1
4 5nj8 21:306 30,124 180,180 P:A,B · DNA:E,F 27.2% / 47.0% 67,32 View · PDB DIMER_tr_X5DRK2_X5DRK2_HUMAN:30:180_5nj8_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
22-81PF23171Hypoxia-inducible factor 1-alpha bHLH domainoverlaps 21-306
122-183PF00989PAS foldoverlaps 21-306